HitPredict

Interactor 1: 1433B (P31946)
14-3-3 protein beta/alpha (Protein 1054) (Protein kinase C inhibitor protein 1) (KCIP-1) [Cleaved into: 14-3-3 protein beta/alpha, N-terminally processed]
Gene: YWHAB

Interactor 2: SRRM2 (Q9UQ35)
Serine/arginine repetitive matrix protein 2 (300 kDa nuclear matrix antigen) (Serine/arginine-rich splicing factor-related nuclear matrix protein of 300 kDa) (SR-related nuclear matrix protein of 300 kDa) (Ser/Arg-related nuclear matrix protein of 300 kDa) (Splicing coactivator subunit SRm300) (Tax-responsive enhancer element-binding protein 803) (TaxREB803)
Gene: SRRM2

Species: Homo sapiens

Source: mint

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.71	0.50	0.599

Property	Details
Experiments	17353931, 36931259, 15324660
Identification Methods	affinity chromatography technology, proximity labelling technology, anti bait coimmunoprecipitation, coimmunoprecipitation
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	-
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 246 Hs			1 2752
+	Hs
		910167 1433E_HUMAN (3-243): 4.39e-144: 405: 65.43		SRRM2_HUMAN (1-2752): 2.88e-178: 615: 100.00
+	Hs
		927666 1433Z_HUMAN (3-244): 1.49e-141: 398: 87.60		SRRM2_HUMAN (1-2752): 2.88e-178: 615: 100.00
+	Hs
		909937 1433E_HUMAN (3-243): 4.39e-144: 405: 65.43		CIC_HUMAN (216-2751): 1.9e-62: 240: 8.98
+	Hs
		683645 1433B_HUMAN (1-246): 3.48e-144: 404: 100.00		CIC_HUMAN (216-2751): 1.9e-62: 240: 8.98
+	Hs
		927430 1433Z_HUMAN (3-244): 1.49e-141: 398: 87.60		CIC_HUMAN (216-2751): 1.9e-62: 240: 8.98
+	Hs
		647206 1433T_HUMAN (3-244): 3.24e-127: 361: 81.82		CIC_HUMAN (216-2751): 1.9e-62: 240: 8.98
+	Hs
		683783 1433B_HUMAN (1-246): 3.48e-144: 404: 100.00		STAR9_HUMAN (764-2750): 1.09e-41: 172: 13.94
+	Hs
		927616 1433Z_HUMAN (3-244): 1.49e-141: 398: 87.60		STAR9_HUMAN (764-2750): 1.09e-41: 172: 13.94
+	Hs
		927352 1433Z_HUMAN (3-244): 1.49e-141: 398: 87.60		TITIN_HUMAN (26-1299): 8.38e-20: 100: 7.11
+	Hs
		820871 1433E_HUMAN (3-243): 4.39e-144: 405: 65.43		PRC2A_HUMAN (8-1230): 6.75e-14: 80.5: 10.65
+	Hs
		311800 1433E_HUMAN (3-243): 4.39e-144: 405: 65.43		TACC2_HUMAN (1893-2744): 4.03e-13: 78.2: 8.34
+	Hs
		820876 1433Z_HUMAN (3-244): 1.49e-141: 398: 87.60		PRC2A_HUMAN (8-1230): 6.75e-14: 80.5: 10.65
+	Hs
		311801 1433Z_HUMAN (3-244): 1.49e-141: 398: 87.60		TACC2_HUMAN (1893-2744): 4.03e-13: 78.2: 8.34
+	Hs
		297821 1433E_HUMAN (3-243): 4.39e-144: 405: 65.43		K0754_HUMAN (864-1413): 2.27e-10: 69.1: 16.44
+	Hs
		297815 1433B_HUMAN (1-246): 3.48e-144: 404: 100.00		K0754_HUMAN (864-1413): 2.27e-10: 69.1: 16.44
+	Hs
		909455 1433E_HUMAN (3-243): 4.39e-144: 405: 65.43		ANK2_HUMAN (1488-2676): 2.26e-09: 65.6: 13.23
+	Hs
		297824 1433Z_HUMAN (3-244): 1.49e-141: 398: 87.60		K0754_HUMAN (864-1413): 2.27e-10: 69.1: 16.44
+	Hs
		926936 1433Z_HUMAN (3-244): 1.49e-141: 398: 87.60		ANK2_HUMAN (1488-2676): 2.26e-09: 65.6: 13.23
+	Hs
		647151 1433T_HUMAN (3-244): 3.24e-127: 361: 81.82		TITIN_HUMAN (26-1299): 8.38e-20: 100: 7.11
+	Hs
		646808 1433T_HUMAN (3-244): 3.24e-127: 361: 81.82		ANK2_HUMAN (1488-2676): 2.26e-09: 65.6: 13.23