HitPredict

Interactor 1: 1433B (P31946)
14-3-3 protein beta/alpha (Protein 1054) (Protein kinase C inhibitor protein 1) (KCIP-1) [Cleaved into: 14-3-3 protein beta/alpha, N-terminally processed]
Gene: YWHAB

Interactor 2: GRIP1 (Q9Y3R0)
Glutamate receptor-interacting protein 1 (GRIP-1)
Gene: GRIP1

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.85	0.60	0.716

Property	Details
Experiments	33961781, 35271311, 36931259, 24255178, 28514442
Identification Methods	affinity chromatography technology, proximity labelling technology, anti tag coimmunoprecipitation
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005829 - cytosol
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 246 Hs			1 1128
+	Hs
		910195 1433E_HUMAN (3-243): 4.39e-144: 405: 65.43		GRIP1_HUMAN (1-1128): 0: 676: 100.00
+	Hs
		927696 1433Z_HUMAN (3-244): 1.49e-141: 398: 87.60		GRIP1_HUMAN (1-1128): 0: 676: 100.00
+	Hs
		910124 1433E_HUMAN (3-243): 4.39e-144: 405: 65.43		ZO2_HUMAN (33-1124): 2.95e-51: 199: 12.79
+	Hs
		683788 1433B_HUMAN (1-246): 3.48e-144: 404: 100.00		ZO2_HUMAN (33-1124): 2.95e-51: 199: 12.79
+	Hs
		927623 1433Z_HUMAN (3-244): 1.49e-141: 398: 87.60		ZO2_HUMAN (33-1124): 2.95e-51: 199: 12.79
+	Hs
		683644 1433B_HUMAN (1-246): 3.48e-144: 404: 100.00		MAGI1_HUMAN (216-1126): 8.38e-41: 166: 12.95
+	Mm
		250606 1433Z_MOUSE (3-244): 3.14e-142: 399: 88.02		LNX1_MOUSE (13-235): 2.92e-29: 127: 23.92
+	Hs
		683339 1433B_HUMAN (1-246): 3.48e-144: 404: 100.00		SCRIB_HUMAN (673-1100): 2.61e-27: 122: 17.81
+	Mm
		250656 1433B_MOUSE (1-246): 5.56e-141: 396: 98.78		LNX1_MOUSE (13-235): 2.92e-29: 127: 23.92
+	Hs
		927034 1433Z_HUMAN (3-244): 1.49e-141: 398: 87.60		SCRIB_HUMAN (673-1100): 2.61e-27: 122: 17.81
+	Hs
		909498 1433E_HUMAN (3-243): 4.39e-144: 405: 65.43		PTN13_HUMAN (18-280): 1.38e-22: 107: 18.56
+	Hs
		683305 1433B_HUMAN (1-246): 3.48e-144: 404: 100.00		PTN13_HUMAN (18-280): 1.38e-22: 107: 18.56
+	Hs
		926984 1433Z_HUMAN (3-244): 1.49e-141: 398: 87.60		PTN13_HUMAN (18-280): 1.38e-22: 107: 18.56
+	Mm
		910260 1433E_MOUSE (3-243): 4.39e-144: 405: 65.43		DLG4_MOUSE (999-1126): 8.76e-15: 81.3: 20.74
+	Mm
		926805 1433Z_MOUSE (3-244): 3.14e-142: 399: 88.02		DLG4_MOUSE (999-1126): 8.76e-15: 81.3: 20.74
+	Mm
		1143489 1433B_MOUSE (1-246): 5.56e-141: 396: 98.78		DLG4_MOUSE (999-1126): 8.76e-15: 81.3: 20.74
+	Dm
		677686 1433E_DROME (3-245): 4.63e-144: 405: 64.90		DLG1_DROME (656-790): 7.8e-11: 68.8: 24.11
+	Hs
		927328 1433Z_HUMAN (3-244): 1.49e-141: 398: 87.60		LNX1_HUMAN (777-1113): 2.02e-11: 70.4: 14.08
+	Mm
		926859 1433Z_MOUSE (3-244): 3.14e-142: 399: 88.02		LNX2_MOUSE (916-1116): 1.03e-10: 67.8: 13.59
+	Dm
		664599 1433Z_DROME (2-246): 4.79e-141: 396: 78.78		DLG1_DROME (656-790): 7.8e-11: 68.8: 24.11