HitPredict

Interactor 1: 1433S (P31947)
14-3-3 protein sigma (Epithelial cell marker protein 1) (Stratifin)
Gene: SFN

Interactor 2: MTOR (P42345)
Serine/threonine-protein kinase mTOR (EC 2.7.11.1) (FK506-binding protein 12-rapamycin complex-associated protein 1) (FKBP12-rapamycin complex-associated protein) (Mammalian target of rapamycin) (mTOR) (Mechanistic target of rapamycin) (Rapamycin and FKBP12 target 1) (Rapamycin target protein 1)
Gene: MTOR

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.38	0.60	0.479

Property	Details
Experiments	36931259
Identification Methods	proximity labelling technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005634 - nucleus GO:0005737 - cytoplasm GO:0005829 - cytosol GO:0030307 - positive regulation of cell growth
Homologous interactions	19

Homologous interactions

Color coding for hit scores

	1 248 Hs			1 2549
+	Hs
		787440 1433E_HUMAN (2-246): 4.41e-146: 410: 60.41		MTOR_HUMAN (1-2549): 0: 2102: 100.00
+	Hs
		787451 1433Z_HUMAN (1-243): 5.4e-136: 384: 70.37		MTOR_HUMAN (1-2549): 0: 2102: 100.00
+	Hs
		646705 1433T_HUMAN (1-238): 9.98e-108: 312: 71.85		MTOR_HUMAN (1-2549): 0: 2102: 100.00
+	Hs
		683184 1433B_HUMAN (1-239): 3.41e-100: 293: 68.62		MTOR_HUMAN (1-2549): 0: 2102: 100.00
+	Hs
		787438 1433G_HUMAN (1-242): 1.86e-98: 289: 65.16		MTOR_HUMAN (1-2549): 0: 2102: 100.00
+	Hs
		787460 1433F_HUMAN (2-242): 2.78e-96: 283: 64.20		MTOR_HUMAN (1-2549): 0: 2102: 100.00
+	Hs
		927004 1433Z_HUMAN (1-243): 5.4e-136: 384: 70.37		ATM_HUMAN (387-2548): 0: 894: 14.98
+	At
		788647 14333_ARATH (3-247): 2.63e-144: 405: 58.30		ATM_ARATH (401-2548): 0: 704: 13.98
+	Hs
		926917 1433Z_HUMAN (1-243): 5.4e-136: 384: 70.37		PRKDC_HUMAN (695-2548): 0: 686: 14.83
+	Hs
		683847 1433B_HUMAN (1-239): 3.41e-100: 293: 68.62		TRRAP_HUMAN (925-2548): 0: 720: 15.53
+	Hs
		905297 1433G_HUMAN (1-242): 1.86e-98: 289: 65.16		TRRAP_HUMAN (925-2548): 0: 720: 15.53
+	Hs
		646792 1433T_HUMAN (1-238): 9.98e-108: 312: 71.85		PRKDC_HUMAN (695-2548): 0: 686: 14.83
+	Hs
		683261 1433B_HUMAN (1-239): 3.41e-100: 293: 68.62		PRKDC_HUMAN (695-2548): 0: 686: 14.83
+	Hs
		904439 1433G_HUMAN (1-242): 1.86e-98: 289: 65.16		PRKDC_HUMAN (695-2548): 0: 686: 14.83
+	Hs
		904645 1433G_HUMAN (1-242): 1.86e-98: 289: 65.16		Q4LE69_HUMAN (733-2453): 1.63e-160: 553: 12.12
+	Hs
		982077 1433F_HUMAN (2-242): 2.78e-96: 283: 64.20		Q4LE69_HUMAN (733-2453): 1.63e-160: 553: 12.12
+	Hs
		927364 1433Z_HUMAN (1-243): 5.4e-136: 384: 70.37		GCN1_HUMAN (245-1372): 1.05e-38: 162: 12.17
+	Hs
		647159 1433T_HUMAN (1-238): 9.98e-108: 312: 71.85		GCN1_HUMAN (245-1372): 1.05e-38: 162: 12.17
+	Dm
		664613 1433Z_DROME (1-245): 4.71e-99: 290: 66.12		Q7K3H0_DROME (1898-2419): 8.48e-26: 119: 19.33