HitPredict

Interactor 1: 1433S (P31947)
14-3-3 protein sigma (Epithelial cell marker protein 1) (Stratifin)
Gene: SFN

Interactor 2: DOC11 (Q5JSL3)
Dedicator of cytokinesis protein 11 (Activated Cdc42-associated guanine nucleotide exchange factor) (ACG) (Zizimin-2)
Gene: DOCK11

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.38	0.60	0.479

Property	Details
Experiments	36931259
Identification Methods	proximity labelling technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005829 - cytosol
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 248 Hs			1 2073
+	Hs
		909638 1433E_HUMAN (2-246): 4.41e-146: 410: 60.41		DOC11_HUMAN (1-2073): 0: 2784: 100.00
+	Hs
		927120 1433Z_HUMAN (1-243): 5.4e-136: 384: 70.37		DOC11_HUMAN (1-2073): 0: 2784: 100.00
+	Hs
		63199 1433Z_HUMAN (1-243): 5.4e-136: 384: 70.37		A6NIW2_HUMAN (1-2073): 0: 2778: 99.81
+	Hs
		646953 1433T_HUMAN (1-238): 9.98e-108: 312: 71.85		DOC11_HUMAN (1-2073): 0: 2784: 100.00
+	Hs
		683403 1433B_HUMAN (1-239): 3.41e-100: 293: 68.62		DOC11_HUMAN (1-2073): 0: 2784: 100.00
+	Hs
		904658 1433G_HUMAN (1-242): 1.86e-98: 289: 65.16		DOC11_HUMAN (1-2073): 0: 2784: 100.00
+	Hs
		909993 1433E_HUMAN (2-246): 4.41e-146: 410: 60.41		DOCK9_HUMAN (2-2035): 0: 2538: 58.90
+	Hs
		927490 1433Z_HUMAN (1-243): 5.4e-136: 384: 70.37		DOCK9_HUMAN (2-2035): 0: 2538: 58.90
+	Hs
		683685 1433B_HUMAN (1-239): 3.41e-100: 293: 68.62		DOCK9_HUMAN (2-2035): 0: 2538: 58.90
+	Hs
		683533 1433B_HUMAN (1-239): 3.41e-100: 293: 68.62		DOCK4_HUMAN (1464-2069): 9.01e-156: 532: 17.36
+	Hs
		904844 1433G_HUMAN (1-242): 1.86e-98: 289: 65.16		DOCK4_HUMAN (1464-2069): 9.01e-156: 532: 17.36
+	Hs
		684270 1433S_HUMAN (1-248): 3.48e-158: 440: 100.00		DOCK7_HUMAN (1-163): 4.93e-49: 195: 31.18
+	Hs
		909920 1433E_HUMAN (2-246): 4.41e-146: 410: 60.41		DOCK7_HUMAN (1-163): 4.93e-49: 195: 31.18
+	Mm
		56981 1433E_MOUSE (2-246): 4.41e-146: 410: 60.41		A2A9M5_MOUSE (1-163): 2.77e-48: 193: 31.18
+	Hs
		927415 1433Z_HUMAN (1-243): 5.4e-136: 384: 70.37		DOCK7_HUMAN (1-163): 4.93e-49: 195: 31.18
+	Mm
		56982 1433Z_MOUSE (1-243): 1.34e-136: 385: 69.96		A2A9M5_MOUSE (1-163): 2.77e-48: 193: 31.18
+	Mm
		910297 1433E_MOUSE (2-246): 4.41e-146: 410: 60.41		DOCK8_MOUSE (2-147): 6.81e-40: 165: 22.09
+	Hs
		108780 1433E_HUMAN (2-246): 4.41e-146: 410: 60.41		H0Y572_HUMAN (1308-1424): 1.06e-35: 134: 54.70
+	Hs
		647195 1433T_HUMAN (1-238): 9.98e-108: 312: 71.85		DOCK7_HUMAN (1-163): 4.93e-49: 195: 31.18
+	Hs
		683630 1433B_HUMAN (1-239): 3.41e-100: 293: 68.62		DOCK7_HUMAN (1-163): 4.93e-49: 195: 31.18