HitPredict

Interactor 1: 1433S (P31947)
14-3-3 protein sigma (Epithelial cell marker protein 1) (Stratifin)
Gene: SFN

Interactor 2: MPRIP (Q6WCQ1)
Myosin phosphatase Rho-interacting protein (M-RIP) (Rho-interacting protein 3) (RIP3) (p116Rip)
Gene: MPRIP

Species: Homo sapiens

Source: mint

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.60	0.60	0.601

Property	Details
Experiments	15778465, 36931259
Identification Methods	affinity chromatography technology, proximity labelling technology, tandem affinity purification
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005829 - cytosol GO:0045296 - cadherin binding
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 248 Hs			1 1025
+	Hs
		909703 1433E_HUMAN (2-246): 4.41e-146: 410: 60.41		MPRIP_HUMAN (1-1025): 9.29e-127: 412: 100.00
+	Mm
		910229 1433E_MOUSE (2-246): 4.41e-146: 410: 60.41		MPRIP_MOUSE (1-1024): 9.38e-118: 388: 88.01
+	Hs
		684200 1433S_HUMAN (1-248): 3.48e-158: 440: 100.00		Q8N236_HUMAN (208-793): 1.05e-47: 182: 100.00
+	Hs
		684115 1433S_HUMAN (1-248): 3.48e-158: 440: 100.00		MRCKG_HUMAN (599-998): 1.13e-44: 178: 19.48
+	Hs
		909845 1433E_HUMAN (2-246): 4.41e-146: 410: 60.41		DLG5_HUMAN (647-1019): 8.88e-54: 207: 21.61
+	Hs
		684119 1433S_HUMAN (1-248): 3.48e-158: 440: 100.00		PKHA7_HUMAN (336-980): 5.04e-41: 166: 13.51
+	Hs
		684333 1433S_HUMAN (1-248): 3.48e-158: 440: 100.00		PKHA5_HUMAN (318-1019): 7.56e-36: 149: 13.24
+	Hs
		909680 1433E_HUMAN (2-246): 4.41e-146: 410: 60.41		PKHA7_HUMAN (336-980): 5.04e-41: 166: 13.51
+	Hs
		910040 1433E_HUMAN (2-246): 4.41e-146: 410: 60.41		PKHA5_HUMAN (318-1019): 7.56e-36: 149: 13.24
+	Hs
		683875 1433S_HUMAN (1-248): 3.48e-158: 440: 100.00		MYH11_HUMAN (124-786): 1.25e-12: 74.7: 11.57
+	Hs
		684048 1433S_HUMAN (1-248): 3.48e-158: 440: 100.00		PLEC_HUMAN (499-978): 3.1e-11: 70.1: 14.96
+	Hs
		725130 1433E_HUMAN (2-246): 4.41e-146: 410: 60.41		MYH10_HUMAN (534-1014): 3.94e-16: 85.9: 9.18
+	Hs
		728460 1433E_HUMAN (2-246): 4.41e-146: 410: 60.41		MYH11_HUMAN (124-786): 1.25e-12: 74.7: 11.57
+	Mm
		926855 1433Z_MOUSE (1-243): 1.34e-136: 385: 69.96		MYH9_MOUSE (542-1025): 4.68e-18: 92.5: 8.68
+	Hs
		724761 1433Z_HUMAN (1-243): 5.4e-136: 384: 70.37		MYH9_HUMAN (540-1015): 1.52e-17: 90.5: 9.66
+	Hs
		522602 1433Z_HUMAN (1-243): 5.4e-136: 384: 70.37		MYH7_HUMAN (101-931): 7.33e-17: 88.6: 10.36
+	Mm
		926804 1433Z_MOUSE (1-243): 1.34e-136: 385: 69.96		MYH10_MOUSE (534-1014): 8.31e-16: 85.1: 9.18
+	Hs
		728466 1433Z_HUMAN (1-243): 5.4e-136: 384: 70.37		MYH11_HUMAN (124-786): 1.25e-12: 74.7: 11.57
+	Mm
		926889 1433Z_MOUSE (1-243): 1.34e-136: 385: 69.96		PLEC_MOUSE (494-979): 2.14e-11: 70.8: 14.60
+	Hs
		927068 1433Z_HUMAN (1-243): 5.4e-136: 384: 70.37		PLEC_HUMAN (499-978): 3.1e-11: 70.1: 14.96