HitPredict

Interactor 1: 1433S (P31947)
14-3-3 protein sigma (Epithelial cell marker protein 1) (Stratifin)
Gene: SFN

Interactor 2: PHLB2 (Q86SQ0)
Pleckstrin homology-like domain family B member 2 (Protein LL5-beta)
Gene: PHLDB2

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.51	0.60	0.554

Property	Details
Experiments	36931259
Identification Methods	affinity chromatography technology, proximity labelling technology, anti tag coimmunoprecipitation
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005829 - cytosol GO:0045296 - cadherin binding
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 248 Hs			1 1253
+	Hs
		909748 1433E_HUMAN (2-246): 4.41e-146: 410: 60.41		PHLB2_HUMAN (1-1253): 7.85e-124: 415: 100.00
+	Hs
		684169 1433S_HUMAN (1-248): 3.48e-158: 440: 100.00		PHLB1_HUMAN (21-1252): 1.6e-69: 258: 28.61
+	Hs
		909755 1433E_HUMAN (2-246): 4.41e-146: 410: 60.41		PHLB1_HUMAN (21-1252): 1.6e-69: 258: 28.61
+	Hs
		317226 1433Z_HUMAN (1-243): 5.4e-136: 384: 70.37		PCNT_HUMAN (193-1114): 4.5e-50: 197: 16.74
+	Hs
		683875 1433S_HUMAN (1-248): 3.48e-158: 440: 100.00		MYH11_HUMAN (486-1136): 4.39e-23: 109: 11.38
+	Hs
		522602 1433Z_HUMAN (1-243): 5.4e-136: 384: 70.37		MYH7_HUMAN (150-1188): 3.75e-36: 152: 9.38
+	Mm
		926804 1433Z_MOUSE (1-243): 1.34e-136: 385: 69.96		MYH10_MOUSE (197-1139): 1.63e-34: 146: 8.45
+	Hs
		909975 1433E_HUMAN (2-246): 4.41e-146: 410: 60.41		CP250_HUMAN (234-1201): 3.48e-24: 113: 8.59
+	Hs
		728460 1433E_HUMAN (2-246): 4.41e-146: 410: 60.41		MYH11_HUMAN (486-1136): 4.39e-23: 109: 11.38
+	Hs
		725130 1433E_HUMAN (2-246): 4.41e-146: 410: 60.41		MYH10_HUMAN (164-906): 2.35e-20: 100: 9.92
+	Hs
		297821 1433E_HUMAN (2-246): 4.41e-146: 410: 60.41		K0754_HUMAN (42-1075): 9.75e-20: 98.6: 8.66
+	Hs
		684048 1433S_HUMAN (1-248): 3.48e-158: 440: 100.00		PLEC_HUMAN (379-991): 1.99e-10: 67.8: 12.17
+	Hs
		502907 1433Z_HUMAN (1-243): 5.4e-136: 384: 70.37		MYH3_HUMAN (195-1037): 5.65e-25: 115: 10.75
+	Mm
		926855 1433Z_MOUSE (1-243): 1.34e-136: 385: 69.96		MYH9_MOUSE (548-1196): 3.27e-24: 113: 10.61
+	Hs
		297824 1433Z_HUMAN (1-243): 5.4e-136: 384: 70.37		K0754_HUMAN (42-1075): 9.75e-20: 98.6: 8.66
+	Mm
		93548 1433E_MOUSE (2-246): 4.41e-146: 410: 60.41		DESP_MOUSE (362-840): 9.43e-11: 68.8: 18.73
+	Hs
		909555 1433E_HUMAN (2-246): 4.41e-146: 410: 60.41		DCTN1_HUMAN (447-912): 5.75e-10: 66.1: 15.78
+	Mm
		926889 1433Z_MOUSE (1-243): 1.34e-136: 385: 69.96		PLEC_MOUSE (370-1115): 4.58e-15: 83.3: 10.64
+	Mm
		926886 1433Z_MOUSE (1-243): 1.34e-136: 385: 69.96		MY18A_MOUSE (415-1127): 2.03e-10: 67.7: 16.06
+	Hs
		551660 1433Z_HUMAN (1-243): 5.4e-136: 384: 70.37		DESP_HUMAN (412-840): 2.66e-10: 67.3: 19.03