HitPredict

Interactor 1: 1433S (P31947)
14-3-3 protein sigma (Epithelial cell marker protein 1) (Stratifin)
Gene: SFN

Interactor 2: PIM3 (Q86V86)
Serine/threonine-protein kinase pim-3 (EC 2.7.11.1)
Gene: PIM3

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.47	0.60	0.536

Property	Details
Experiments	32707033
Identification Methods	affinity chromatography technology, pull down
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005737 - cytoplasm GO:0005829 - cytosol
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 248 Hs			1 326
+	Hs
		647836 1433S_HUMAN (1-248): 3.48e-158: 440: 100.00		MARK3_HUMAN (4-324): 3.45e-124: 374: 25.00
+	Hs
		684157 1433S_HUMAN (1-248): 3.48e-158: 440: 100.00		MARK2_HUMAN (12-318): 3.13e-123: 373: 27.30
+	Hs
		681682 1433S_HUMAN (1-248): 3.48e-158: 440: 100.00		AKT1_HUMAN (11-323): 2.69e-123: 363: 23.03
+	Mm
		910231 1433E_MOUSE (2-246): 4.41e-146: 410: 60.41		MARK3_MOUSE (4-324): 3.1e-124: 375: 25.31
+	Hs
		647862 1433E_HUMAN (2-246): 4.41e-146: 410: 60.41		MARK3_HUMAN (4-324): 3.45e-124: 374: 25.00
+	Hs
		683925 1433S_HUMAN (1-248): 3.48e-158: 440: 100.00		SIK1_HUMAN (40-305): 1.75e-110: 340: 31.87
+	At
		1280891 14337_ARATH (2-247): 4.35e-147: 413: 58.07		CIPKC_ARATH (20-325): 4.32e-124: 366: 27.22
+	Mm
		910234 1433E_MOUSE (2-246): 4.41e-146: 410: 60.41		MARK2_MOUSE (12-318): 7.85e-122: 369: 26.98
+	Hs
		681770 1433E_HUMAN (2-246): 4.41e-146: 410: 60.41		AKT1_HUMAN (11-323): 2.69e-123: 363: 23.03
+	Hs
		568616 1433E_HUMAN (2-246): 4.41e-146: 410: 60.41		KAPCA_HUMAN (28-325): 2.63e-123: 359: 24.36
+	Mm
		910308 1433E_MOUSE (2-246): 4.41e-146: 410: 60.41		MARK4_MOUSE (31-293): 1.31e-110: 339: 28.52
+	Hs
		684192 1433S_HUMAN (1-248): 3.48e-158: 440: 100.00		BRSK2_HUMAN (31-321): 4.06e-35: 137: 30.84
+	Hs
		684316 1433S_HUMAN (1-248): 3.48e-158: 440: 100.00		SIK2_HUMAN (40-294): 8.16e-34: 133: 32.82
+	Hs
		684349 1433S_HUMAN (1-248): 3.48e-158: 440: 100.00		SNRK_HUMAN (40-297): 2.06e-33: 132: 33.46
+	Hs
		684313 1433S_HUMAN (1-248): 3.48e-158: 440: 100.00		NUAK2_HUMAN (33-293): 1.99e-32: 128: 32.96
+	Hs
		684274 1433S_HUMAN (1-248): 3.48e-158: 440: 100.00		TSSK2_HUMAN (37-293): 7.42e-33: 126: 32.84
+	Mm
		910248 1433E_MOUSE (2-246): 4.41e-146: 410: 60.41		BRSK1_MOUSE (40-304): 1.27e-37: 144: 34.19
+	Mm
		910272 1433E_MOUSE (2-246): 4.41e-146: 410: 60.41		BRSK2_MOUSE (31-321): 1.08e-35: 138: 31.17
+	Hs
		229938 1433E_HUMAN (2-246): 4.41e-146: 410: 60.41		NUAK1_HUMAN (33-293): 5.1e-34: 133: 31.23
+	Mm
		910266 1433E_MOUSE (2-246): 4.41e-146: 410: 60.41		NUAK1_MOUSE (33-293): 5.29e-34: 133: 31.25