HitPredict

Interactor 1: 1433S (P31947)
14-3-3 protein sigma (Epithelial cell marker protein 1) (Stratifin)
Gene: SFN

Interactor 2: LIPB1 (Q86W92)
Liprin-beta-1 (Protein tyrosine phosphatase receptor type f polypeptide-interacting protein-binding protein 1) (PTPRF-interacting protein-binding protein 1) (hSGT2)
Gene: PPFIBP1

Species: Homo sapiens

Source: mint

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.62	0.60	0.612

Property	Details
Experiments	15778465, 36931259
Identification Methods	affinity chromatography technology, proximity labelling technology, cross-linking study, tandem affinity purification
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005829 - cytosol GO:0045296 - cadherin binding
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 248 Hs			1 1011
+	Hs
		909765 1433E_HUMAN (2-246): 4.41e-146: 410: 60.41		LIPB1_HUMAN (1-1011): 7.51e-135: 433: 100.00
+	Hs
		684244 1433S_HUMAN (1-248): 3.48e-158: 440: 100.00		ANS1A_HUMAN (502-904): 1.42e-45: 180: 15.23
+	Hs
		909875 1433E_HUMAN (2-246): 4.41e-146: 410: 60.41		ANS1A_HUMAN (502-904): 1.42e-45: 180: 15.23
+	Hs
		684102 1433S_HUMAN (1-248): 3.48e-158: 440: 100.00		MRCKA_HUMAN (50-632): 1.12e-35: 149: 15.57
+	Hs
		909658 1433E_HUMAN (2-246): 4.41e-146: 410: 60.41		MRCKA_HUMAN (50-632): 1.12e-35: 149: 15.57
+	Hs
		725130 1433E_HUMAN (2-246): 4.41e-146: 410: 60.41		MYH10_HUMAN (2-784): 3.65e-29: 128: 8.24
+	Hs
		684215 1433S_HUMAN (1-248): 3.48e-158: 440: 100.00		LIPB2_HUMAN (1-360): 1.13e-17: 90.7: 45.48
+	Hs
		683875 1433S_HUMAN (1-248): 3.48e-158: 440: 100.00		MYH11_HUMAN (2-530): 1.42e-16: 87.6: 9.26
+	Mm
		926804 1433Z_MOUSE (1-243): 1.34e-136: 385: 69.96		MYH10_MOUSE (2-781): 7.75e-31: 133: 10.05
+	Mm
		926855 1433Z_MOUSE (1-243): 1.34e-136: 385: 69.96		MYH9_MOUSE (2-781): 1.27e-30: 133: 8.27
+	Hs
		684115 1433S_HUMAN (1-248): 3.48e-158: 440: 100.00		MRCKG_HUMAN (10-430): 3.09e-13: 76.5: 14.45
+	Hs
		684010 1433S_HUMAN (1-248): 3.48e-158: 440: 100.00		LIPA1_HUMAN (1-598): 1.48e-09: 64.2: 9.82
+	Hs
		909824 1433E_HUMAN (2-246): 4.41e-146: 410: 60.41		LIPB2_HUMAN (1-360): 1.13e-17: 90.7: 45.48
+	Hs
		728460 1433E_HUMAN (2-246): 4.41e-146: 410: 60.41		MYH11_HUMAN (2-530): 1.42e-16: 87.6: 9.26
+	Mm
		910258 1433E_MOUSE (2-246): 4.41e-146: 410: 60.41		KINH_MOUSE (128-514): 3.14e-11: 69.6: 12.63
+	Hs
		909508 1433E_HUMAN (2-246): 4.41e-146: 410: 60.41		LIPA1_HUMAN (1-598): 1.48e-09: 64.2: 9.82
+	Hs
		502907 1433Z_HUMAN (1-243): 5.4e-136: 384: 70.37		MYH3_HUMAN (18-342): 1.75e-11: 70.7: 7.69
+	Mm
		926803 1433Z_MOUSE (1-243): 1.34e-136: 385: 69.96		KINH_MOUSE (128-514): 3.14e-11: 69.6: 12.63
+	Mm
		890551 1433Z_MOUSE (1-243): 1.34e-136: 385: 69.96		LIPA3_MOUSE (195-655): 2.66e-10: 66.9: 9.09
+	Mm
		926835 1433Z_MOUSE (1-243): 1.34e-136: 385: 69.96		LIPA2_MOUSE (28-642): 2.75e-10: 66.9: 7.99