HitPredict

Interactor 1: 1433S (P31947)
14-3-3 protein sigma (Epithelial cell marker protein 1) (Stratifin)
Gene: SFN

Interactor 2: RGPS2 (Q86X27)
Ras-specific guanine nucleotide-releasing factor RalGPS2 (Ral GEF with PH domain and SH3-binding motif 2) (RalA exchange factor RalGPS2)
Gene: RALGPS2

Species: Homo sapiens

Source: mint

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.60	0.60	0.601

Property	Details
Experiments	15778465, 36931259
Identification Methods	affinity chromatography technology, cross-linking study, tandem affinity purification
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005737 - cytoplasm
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 248 Hs			1 583
+	Hs
		909770 1433E_HUMAN (2-246): 4.41e-146: 410: 60.41		RGPS2_HUMAN (1-583): 0: 643: 100.00
+	Hs
		927257 1433Z_HUMAN (1-243): 5.4e-136: 384: 70.37		RGPS2_HUMAN (1-583): 0: 643: 100.00
+	Hs
		647073 1433T_HUMAN (1-238): 9.98e-108: 312: 71.85		RGPS2_HUMAN (1-583): 0: 643: 100.00
+	Hs
		683515 1433B_HUMAN (1-239): 3.41e-100: 293: 68.62		RGPS2_HUMAN (1-583): 0: 643: 100.00
+	Hs
		684227 1433S_HUMAN (1-248): 3.48e-158: 440: 100.00		RPGF6_HUMAN (18-462): 3.55e-96: 323: 15.79
+	Hs
		910200 1433E_HUMAN (2-246): 4.41e-146: 410: 60.41		RPGF2_HUMAN (18-474): 8.7e-102: 339: 17.58
+	Hs
		171544 1433E_HUMAN (2-246): 4.41e-146: 410: 60.41		RGL2_HUMAN (26-480): 5.4e-102: 327: 20.83
+	Hs
		909851 1433E_HUMAN (2-246): 4.41e-146: 410: 60.41		RPGF6_HUMAN (18-462): 3.55e-96: 323: 15.79
+	Hs
		927702 1433Z_HUMAN (1-243): 5.4e-136: 384: 70.37		RPGF2_HUMAN (18-474): 8.7e-102: 339: 17.58
+	Mm
		926845 1433Z_MOUSE (1-243): 1.34e-136: 385: 69.96		RPGF2_MOUSE (18-474): 1.88e-98: 329: 17.58
+	Hs
		927336 1433Z_HUMAN (1-243): 5.4e-136: 384: 70.37		RPGF6_HUMAN (18-462): 3.55e-96: 323: 15.79
+	Mm
		926773 1433Z_MOUSE (1-243): 1.34e-136: 385: 69.96		RGRF2_MOUSE (6-290): 1.89e-90: 304: 29.02
+	Hs
		647081 1433T_HUMAN (1-238): 9.98e-108: 312: 71.85		GRP3_HUMAN (2-480): 8.48e-121: 374: 21.15
+	Hs
		647416 1433T_HUMAN (1-238): 9.98e-108: 312: 71.85		RPGF2_HUMAN (18-474): 8.7e-102: 339: 17.58
+	Hs
		171537 1433T_HUMAN (1-238): 9.98e-108: 312: 71.85		RGL2_HUMAN (26-480): 5.4e-102: 327: 20.83
+	Hs
		647134 1433T_HUMAN (1-238): 9.98e-108: 312: 71.85		RPGF6_HUMAN (18-462): 3.55e-96: 323: 15.79
+	Hs
		683851 1433B_HUMAN (1-239): 3.41e-100: 293: 68.62		RPGF2_HUMAN (18-474): 8.7e-102: 339: 17.58
+	Hs
		171538 1433B_HUMAN (1-239): 3.41e-100: 293: 68.62		RGL2_HUMAN (26-480): 5.4e-102: 327: 20.83
+	Hs
		683569 1433B_HUMAN (1-239): 3.41e-100: 293: 68.62		RPGF6_HUMAN (18-462): 3.55e-96: 323: 15.79
+	Hs
		683335 1433B_HUMAN (1-239): 3.41e-100: 293: 68.62		RGRF1_HUMAN (6-290): 2.79e-89: 302: 28.67