HitPredict

Interactor 1: 1433S (P31947)
14-3-3 protein sigma (Epithelial cell marker protein 1) (Stratifin)
Gene: SFN

Interactor 2: LMTK2 (Q8IWU2)
Serine/threonine-protein kinase LMTK2 (EC 2.7.11.1) (Apoptosis-associated tyrosine kinase 2) (Brain-enriched kinase) (hBREK) (CDK5/p35-regulated kinase) (CPRK) (Kinase/phosphatase/inhibitor 2) (Lemur tyrosine kinase 2) (Serine/threonine-protein kinase KPI-2)
Gene: LMTK2

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.38	0.80	0.553

Property	Details
Experiments	36931259
Identification Methods	proximity labelling technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	14-3-3~PK_Tyr_Ser-Thr
Common GO terms	-
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 248 Hs			1 1503
+	Hs
		684206 1433S_HUMAN (1-248): 3.48e-158: 440: 100.00		MINK1_HUMAN (116-1179): 3.76e-138: 461: 11.73
+	Hs
		683884 1433S_HUMAN (1-248): 3.48e-158: 440: 100.00		ABL2_HUMAN (68-1028): 5.61e-138: 457: 15.48
+	Hs
		684051 1433S_HUMAN (1-248): 3.48e-158: 440: 100.00		ERBB4_HUMAN (17-748): 3.15e-132: 444: 18.30
+	Hs
		789053 1433E_HUMAN (2-246): 4.41e-146: 410: 60.41		ABL2_HUMAN (68-1028): 5.61e-138: 457: 15.48
+	Hs
		337367 1433S_HUMAN (1-248): 3.48e-158: 440: 100.00		ABL1_HUMAN (84-931): 1.76e-117: 399: 18.90
+	Hs
		684033 1433S_HUMAN (1-248): 3.48e-158: 440: 100.00		FAK2_HUMAN (66-696): 3.04e-118: 398: 17.76
+	At
		1277300 14337_ARATH (2-247): 4.35e-147: 413: 58.07		SERK1_ARATH (1-436): 4.18e-129: 416: 18.94
+	Hs
		169164 1433S_HUMAN (1-248): 3.48e-158: 440: 100.00		MUSK_HUMAN (18-420): 2.36e-110: 373: 23.19
+	Hs
		337416 1433E_HUMAN (2-246): 4.41e-146: 410: 60.41		ABL1_HUMAN (84-931): 1.76e-117: 399: 18.90
+	Hs
		169169 1433E_HUMAN (2-246): 4.41e-146: 410: 60.41		MUSK_HUMAN (18-420): 2.36e-110: 373: 23.19
+	Hs
		384358 1433S_HUMAN (1-248): 3.48e-158: 440: 100.00		NTRK1_HUMAN (131-410): 1.29e-36: 152: 33.33
+	Hs
		411316 1433S_HUMAN (1-248): 3.48e-158: 440: 100.00		INSR_HUMAN (93-407): 2.85e-34: 145: 32.82
+	Hs
		435554 1433S_HUMAN (1-248): 3.48e-158: 440: 100.00		IGF1R_HUMAN (131-399): 1.23e-33: 144: 33.33
+	Hs
		683994 1433S_HUMAN (1-248): 3.48e-158: 440: 100.00		ITK_HUMAN (137-407): 1.91e-32: 137: 34.19
+	Hs
		684060 1433S_HUMAN (1-248): 3.48e-158: 440: 100.00		NTRK3_HUMAN (131-410): 1.24e-31: 136: 28.25
+	Hs
		683911 1433S_HUMAN (1-248): 3.48e-158: 440: 100.00		BMX_HUMAN (131-411): 1.01e-31: 135: 31.56
+	Hs
		384604 1433E_HUMAN (2-246): 4.41e-146: 410: 60.41		NTRK1_HUMAN (131-410): 1.29e-36: 152: 33.33
+	Hs
		435597 1433E_HUMAN (2-246): 4.41e-146: 410: 60.41		IGF1R_HUMAN (131-399): 1.23e-33: 144: 33.33
+	Hs
		909481 1433E_HUMAN (2-246): 4.41e-146: 410: 60.41		ITK_HUMAN (137-407): 1.91e-32: 137: 34.19
+	Hs
		850732 1433E_HUMAN (2-246): 4.41e-146: 410: 60.41		BMX_HUMAN (131-411): 1.01e-31: 135: 31.56