HitPredict

Interactor 1: 1433S (P31947)
14-3-3 protein sigma (Epithelial cell marker protein 1) (Stratifin)
Gene: SFN

Interactor 2: RPGF6 (Q8TEU7)
Rap guanine nucleotide exchange factor 6 (PDZ domain-containing guanine nucleotide exchange factor 2) (PDZ-GEF2) (RA-GEF-2)
Gene: RAPGEF6

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.38	0.60	0.479

Property	Details
Experiments	36931259
Identification Methods	proximity labelling technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005829 - cytosol
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 248 Hs			1 1601
+	Hs
		909851 1433E_HUMAN (2-246): 4.41e-146: 410: 60.41		RPGF6_HUMAN (1-1601): 0: 1379: 100.00
+	Hs
		927336 1433Z_HUMAN (1-243): 5.4e-136: 384: 70.37		RPGF6_HUMAN (1-1601): 0: 1379: 100.00
+	Hs
		647134 1433T_HUMAN (1-238): 9.98e-108: 312: 71.85		RPGF6_HUMAN (1-1601): 0: 1379: 100.00
+	Hs
		683569 1433B_HUMAN (1-239): 3.41e-100: 293: 68.62		RPGF6_HUMAN (1-1601): 0: 1379: 100.00
+	Hs
		904905 1433G_HUMAN (1-242): 1.86e-98: 289: 65.16		RPGF6_HUMAN (1-1601): 0: 1379: 100.00
+	Hs
		683335 1433B_HUMAN (1-239): 3.41e-100: 293: 68.62		RGRF1_HUMAN (283-1102): 5.31e-156: 511: 16.08
+	Hs
		684179 1433S_HUMAN (1-248): 3.48e-158: 440: 100.00		RGPS2_HUMAN (813-1273): 6e-81: 281: 16.49
+	Hs
		909770 1433E_HUMAN (2-246): 4.41e-146: 410: 60.41		RGPS2_HUMAN (813-1273): 6e-81: 281: 16.49
+	Hs
		927257 1433Z_HUMAN (1-243): 5.4e-136: 384: 70.37		RGPS2_HUMAN (813-1273): 6e-81: 281: 16.49
+	Hs
		647073 1433T_HUMAN (1-238): 9.98e-108: 312: 71.85		RGPS2_HUMAN (813-1273): 6e-81: 281: 16.49
+	Hs
		683515 1433B_HUMAN (1-239): 3.41e-100: 293: 68.62		RGPS2_HUMAN (813-1273): 6e-81: 281: 16.49
+	Hs
		904810 1433G_HUMAN (1-242): 1.86e-98: 289: 65.16		RGPS2_HUMAN (813-1273): 6e-81: 281: 16.49
+	Mm
		926773 1433Z_MOUSE (1-243): 1.34e-136: 385: 69.96		RGRF2_MOUSE (281-544): 6.95e-44: 177: 14.61
+	Hs
		647081 1433T_HUMAN (1-238): 9.98e-108: 312: 71.85		GRP3_HUMAN (856-1062): 1.91e-61: 226: 25.71
+	Hs
		910200 1433E_HUMAN (2-246): 4.41e-146: 410: 60.41		RPGF2_HUMAN (9-152): 6.41e-11: 69.7: 17.65
+	Mm
		926845 1433Z_MOUSE (1-243): 1.34e-136: 385: 69.96		RPGF2_MOUSE (9-152): 6.41e-11: 69.7: 17.65
+	Hs
		927702 1433Z_HUMAN (1-243): 5.4e-136: 384: 70.37		RPGF2_HUMAN (9-152): 6.41e-11: 69.7: 17.65
+	Hs
		647416 1433T_HUMAN (1-238): 9.98e-108: 312: 71.85		RPGF2_HUMAN (9-152): 6.41e-11: 69.7: 17.65
+	Hs
		683851 1433B_HUMAN (1-239): 3.41e-100: 293: 68.62		RPGF2_HUMAN (9-152): 6.41e-11: 69.7: 17.65
+	Hs
		905302 1433G_HUMAN (1-242): 1.86e-98: 289: 65.16		RPGF2_HUMAN (9-152): 6.41e-11: 69.7: 17.65