HitPredict

Interactor 1: RUXGL (A8MWD9)
Putative small nuclear ribonucleoprotein G-like protein 15
Gene: SNRPGP15

Interactor 2: SF3A1 (Q15459)
Splicing factor 3A subunit 1 (SF3a120) (Spliceosome-associated protein 114) (SAP 114)
Gene: SF3A1

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.33	0.60	0.445

Property	Details
Experiments	28514442
Identification Methods	anti tag coimmunoprecipitation
Interaction Type	association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0000398 - mRNA splicing, via spliceosome GO:0003723 - RNA binding GO:0005686 - U2 snRNP GO:0071004 - U2-type prespliceosome GO:0071013 - catalytic step 2 spliceosome
Homologous interactions	10

Homologous interactions

Color coding for hit scores

	1 76 Hs			1 793
+	Hs
		912049 RUXG_HUMAN (1-76): 5.34e-30: 102: 94.74		SF3A1_HUMAN (1-793): 1.4e-107: 349: 100.00
+	Hs
		912228 LSM6_HUMAN (4-75): 2.84e-27: 95.6: 25.00		SF3A1_HUMAN (1-793): 1.4e-107: 349: 100.00
+	Hs
		1074259 LSM7_HUMAN (3-76): 1.31e-24: 89.8: 31.71		SF3A1_HUMAN (1-793): 1.4e-107: 349: 100.00
+	Hs
		927959 RSMN_HUMAN (1-70): 9.31e-23: 88.6: 21.25		SF3A1_HUMAN (1-793): 1.4e-107: 349: 100.00
+	Hs
		911845 RUXF_HUMAN (5-73): 9.05e-24: 87.1: 26.09		SF3A1_HUMAN (1-793): 1.4e-107: 349: 100.00
+	Hs
		538972 RSMB_HUMAN (1-70): 5.01e-22: 86.7: 21.25		SF3A1_HUMAN (1-793): 1.4e-107: 349: 100.00
+	Sc
		692404 RUXG_YEAST (7-76): 5.33e-22: 82.3: 50.69		PRP21_YEAST (48-340): 6.51e-49: 176: 20.68
+	Sc
		692415 RUXF_YEAST (5-73): 2.81e-21: 80.6: 24.29		PRP21_YEAST (48-340): 6.51e-49: 176: 20.68
+	Sc
		692416 LSM3_YEAST (4-72): 4.33e-10: 52.6: 28.57		PRP21_YEAST (48-340): 6.51e-49: 176: 20.68
+	Hs
		297811 RSMB_HUMAN (1-70): 5.01e-22: 86.7: 21.25		K0754_HUMAN (295-761): 2.54e-20: 99.2: 14.29