HitPredict

Interactor 1: 1433S (P31947)
14-3-3 protein sigma (Epithelial cell marker protein 1) (Stratifin)
Gene: SFN

Interactor 2: LRC59 (Q96AG4)
Leucine-rich repeat-containing protein 59 (Ribosome-binding protein p34) (p34) [Cleaved into: Leucine-rich repeat-containing protein 59, N-terminally processed]
Gene: LRRC59

Species: Homo sapiens

Source: biogrid

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.38	0.60	0.479

Property	Details
Experiments	17361185
Identification Methods	affinity chromatography technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005737 - cytoplasm GO:0007165 - signal transduction GO:0045296 - cadherin binding
Homologous interactions	19

Homologous interactions

Color coding for hit scores

	1 248 Hs			1 307
+	Hs
		684030 1433S_HUMAN (1-248): 3.48e-158: 440: 100.00		SCRIB_HUMAN (24-234): 1.09e-23: 103: 20.85
+	Hs
		684283 1433S_HUMAN (1-248): 3.48e-158: 440: 100.00		ERBIN_HUMAN (41-129): 1.71e-15: 78.9: 31.11
+	At
		788683 14333_ARATH (3-247): 2.63e-144: 405: 58.30		BRL2_ARATH (18-191): 6.04e-20: 92.3: 19.05
+	At
		965375 14332_ARATH (3-248): 2.23e-144: 405: 58.47		BRL2_ARATH (18-191): 6.04e-20: 92.3: 19.05
+	Hs
		910166 1433E_HUMAN (2-246): 4.41e-146: 410: 60.41		SHOC2_HUMAN (6-150): 4.89e-18: 86.3: 22.76
+	Hs
		909939 1433E_HUMAN (2-246): 4.41e-146: 410: 60.41		ERBIN_HUMAN (41-129): 1.71e-15: 78.9: 31.11
+	Hs
		927034 1433Z_HUMAN (1-243): 5.4e-136: 384: 70.37		SCRIB_HUMAN (24-234): 1.09e-23: 103: 20.85
+	At
		788442 14331_ARATH (3-241): 4.5e-144: 405: 56.85		EMS1_ARATH (2-80): 9.42e-12: 67.6: 28.40
+	At
		788640 14333_ARATH (3-247): 2.63e-144: 405: 58.30		EMS1_ARATH (2-80): 9.42e-12: 67.6: 28.40
+	Hs
		927431 1433Z_HUMAN (1-243): 5.4e-136: 384: 70.37		ERBIN_HUMAN (41-129): 1.71e-15: 78.9: 31.11
+	Hs
		646881 1433T_HUMAN (1-238): 9.98e-108: 312: 71.85		SCRIB_HUMAN (24-234): 1.09e-23: 103: 20.85
+	Hs
		683339 1433B_HUMAN (1-239): 3.41e-100: 293: 68.62		SCRIB_HUMAN (24-234): 1.09e-23: 103: 20.85
+	Hs
		904552 1433G_HUMAN (1-242): 1.86e-98: 289: 65.16		SCRIB_HUMAN (24-234): 1.09e-23: 103: 20.85
+	Hs
		647208 1433T_HUMAN (1-238): 9.98e-108: 312: 71.85		ERBIN_HUMAN (41-129): 1.71e-15: 78.9: 31.11
+	Hs
		982003 1433F_HUMAN (2-242): 2.78e-96: 283: 64.20		SCRIB_HUMAN (24-234): 1.09e-23: 103: 20.85
+	Hs
		683820 1433B_HUMAN (1-239): 3.41e-100: 293: 68.62		SHOC2_HUMAN (6-150): 4.89e-18: 86.3: 22.76
+	Hs
		683646 1433B_HUMAN (1-239): 3.41e-100: 293: 68.62		ERBIN_HUMAN (41-129): 1.71e-15: 78.9: 31.11
+	Hs
		905018 1433G_HUMAN (1-242): 1.86e-98: 289: 65.16		ERBIN_HUMAN (41-129): 1.71e-15: 78.9: 31.11
+	Hs
		982410 1433F_HUMAN (2-242): 2.78e-96: 283: 64.20		ERBIN_HUMAN (41-129): 1.71e-15: 78.9: 31.11