HitPredict

Interactor 1: 1433S (P31947)
14-3-3 protein sigma (Epithelial cell marker protein 1) (Stratifin)
Gene: SFN

Interactor 2: KLC2 (Q9H0B6)
Kinesin light chain 2 (KLC 2)
Gene: KLC2

Species: Homo sapiens

Source: mint

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.62	0.60	0.612

Property	Details
Experiments	15778465, 36931259
Identification Methods	affinity chromatography technology, proximity labelling technology, cross-linking study, tandem affinity purification
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005737 - cytoplasm GO:0005829 - cytosol GO:0045296 - cadherin binding
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 248 Hs			1 622
+	Hs
		910010 1433E_HUMAN (2-246): 4.41e-146: 410: 60.41		KLC2_HUMAN (1-622): 1.59e-128: 393: 100.00
+	Hs
		927508 1433Z_HUMAN (1-243): 5.4e-136: 384: 70.37		KLC2_HUMAN (1-622): 1.59e-128: 393: 100.00
+	Hs
		684352 1433S_HUMAN (1-248): 3.48e-158: 440: 100.00		KLC4_HUMAN (7-618): 1.11e-105: 334: 69.13
+	Hs
		910078 1433E_HUMAN (2-246): 4.41e-146: 410: 60.41		KLC4_HUMAN (7-618): 1.11e-105: 334: 69.13
+	Mm
		910337 1433E_MOUSE (2-246): 4.41e-146: 410: 60.41		KLC4_MOUSE (7-618): 1.34e-101: 323: 67.69
+	Hs
		927575 1433Z_HUMAN (1-243): 5.4e-136: 384: 70.37		KLC4_HUMAN (7-618): 1.11e-105: 334: 69.13
+	Hs
		174775 1433E_HUMAN (2-246): 4.41e-146: 410: 60.41		OGT1_HUMAN (58-526): 3.14e-51: 192: 16.63
+	Mm
		910304 1433E_MOUSE (2-246): 4.41e-146: 410: 60.41		OGT1_MOUSE (58-526): 2.65e-51: 192: 16.63
+	Hs
		174785 1433Z_HUMAN (1-243): 5.4e-136: 384: 70.37		OGT1_HUMAN (58-526): 3.14e-51: 192: 16.63
+	At
		788447 14331_ARATH (3-241): 4.5e-144: 405: 56.85		SEC_ARATH (4-455): 2.1e-38: 154: 16.15
+	Hs
		684131 1433S_HUMAN (1-248): 3.48e-158: 440: 100.00		KLC3_HUMAN (363-616): 1.47e-16: 84.7: 21.78
+	Hs
		909889 1433E_HUMAN (2-246): 4.41e-146: 410: 60.41		TTC28_HUMAN (203-568): 1.33e-20: 99: 11.03
+	Hs
		683990 1433S_HUMAN (1-248): 3.48e-158: 440: 100.00		KLC1_HUMAN (406-586): 8.56e-10: 63.5: 12.50
+	Hs
		909688 1433E_HUMAN (2-246): 4.41e-146: 410: 60.41		KLC3_HUMAN (363-616): 1.47e-16: 84.7: 21.78
+	Hs
		927384 1433Z_HUMAN (1-243): 5.4e-136: 384: 70.37		TTC28_HUMAN (203-568): 1.33e-20: 99: 11.03
+	Hs
		909475 1433E_HUMAN (2-246): 4.41e-146: 410: 60.41		KLC1_HUMAN (406-586): 8.56e-10: 63.5: 12.50
+	Hs
		927177 1433Z_HUMAN (1-243): 5.4e-136: 384: 70.37		KLC3_HUMAN (363-616): 1.47e-16: 84.7: 21.78
+	Hs
		926963 1433Z_HUMAN (1-243): 5.4e-136: 384: 70.37		KLC1_HUMAN (406-586): 8.56e-10: 63.5: 12.50
+	Hs
		647010 1433T_HUMAN (1-238): 9.98e-108: 312: 71.85		KLC3_HUMAN (363-616): 1.47e-16: 84.7: 21.78
+	Hs
		646831 1433T_HUMAN (1-238): 9.98e-108: 312: 71.85		KLC1_HUMAN (406-586): 8.56e-10: 63.5: 12.50