HitPredict

Interactor 1: 1433S (P31947)
14-3-3 protein sigma (Epithelial cell marker protein 1) (Stratifin)
Gene: SFN

Interactor 2: HDAC9 (Q9UKV0)
Histone deacetylase 9 (HD9) (EC 3.5.1.98) (Histone deacetylase 7B) (HD7) (HD7b) (Histone deacetylase-related protein) (MEF2-interacting transcription repressor MITR)
Gene: HDAC9

Species: Homo sapiens

Source: biogrid

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.38	0.60	0.479

Property	Details
Experiments	15166223
Identification Methods	affinity chromatography technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0000122 - negative regulation of transcription by RNA polymerase II GO:0005634 - nucleus GO:0005737 - cytoplasm
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 248 Hs			1 1011
+	Hs
		910144 1433E_HUMAN (2-246): 4.41e-146: 410: 60.41		HDAC9_HUMAN (1-1011): 0: 799: 100.00
+	Hs
		683923 1433S_HUMAN (1-248): 3.48e-158: 440: 100.00		HDAC4_HUMAN (1-1009): 0: 691: 54.67
+	Hs
		880661 1433E_HUMAN (2-246): 4.41e-146: 410: 60.41		HDAC4_HUMAN (1-1009): 0: 691: 54.67
+	Hs
		880673 1433Z_HUMAN (1-243): 5.4e-136: 384: 70.37		HDAC4_HUMAN (1-1009): 0: 691: 54.67
+	Hs
		684405 1433S_HUMAN (1-248): 3.48e-158: 440: 100.00		HDAC5_HUMAN (1-1008): 0: 612: 55.67
+	Mm
		250870 1433S_MOUSE (1-248): 4.84e-154: 429: 97.58		Q3UJF1_MOUSE (1-1008): 0: 609: 54.42
+	Mm
		250879 1433S_MOUSE (1-248): 4.84e-154: 429: 97.58		HDAC5_MOUSE (1-1008): 0: 606: 53.75
+	Hs
		910173 1433E_HUMAN (2-246): 4.41e-146: 410: 60.41		HDAC5_HUMAN (1-1008): 0: 612: 55.67
+	Mm
		910239 1433E_MOUSE (2-246): 4.41e-146: 410: 60.41		Q3UJF1_MOUSE (1-1008): 0: 609: 54.42
+	Mm
		910352 1433E_MOUSE (2-246): 4.41e-146: 410: 60.41		HDAC5_MOUSE (1-1008): 0: 606: 53.75
+	Hs
		684233 1433S_HUMAN (1-248): 3.48e-158: 440: 100.00		HDAC7_HUMAN (75-1008): 1.75e-170: 525: 41.57
+	Hs
		909856 1433E_HUMAN (2-246): 4.41e-146: 410: 60.41		HDAC7_HUMAN (75-1008): 1.75e-170: 525: 41.57
+	Hs
		927340 1433Z_HUMAN (1-243): 5.4e-136: 384: 70.37		HDAC7_HUMAN (75-1008): 1.75e-170: 525: 41.57
+	Mm
		910299 1433E_MOUSE (2-246): 4.41e-146: 410: 60.41		HDAC7_MOUSE (71-1008): 2.68e-155: 485: 41.45
+	Hs
		909530 1433E_HUMAN (2-246): 4.41e-146: 410: 60.41		HDAC1_HUMAN (623-1009): 3.2e-140: 430: 23.49
+	At
		817061 14310_ARATH (2-247): 2.9e-137: 387: 53.63		HDA5_ARATH (607-1009): 9.34e-140: 436: 36.65
+	Hs
		177251 1433E_HUMAN (2-246): 4.41e-146: 410: 60.41		HDAC3_HUMAN (631-1007): 9.3e-131: 404: 22.34
+	Hs
		927372 1433Z_HUMAN (1-243): 5.4e-136: 384: 70.37		HDAC2_HUMAN (622-1009): 4.74e-130: 404: 22.67
+	Hs
		910121 1433E_HUMAN (2-246): 4.41e-146: 410: 60.41		HDAC6_HUMAN (564-1009): 2e-107: 363: 30.95
+	Hs
		927619 1433Z_HUMAN (1-243): 5.4e-136: 384: 70.37		HDAC6_HUMAN (564-1009): 2e-107: 363: 30.95