HitPredict

Interactor 1: STIP1 (P31948)
Stress-induced-phosphoprotein 1 (STI1) (Hsc70/Hsp90-organizing protein) (Hop) (Renal carcinoma antigen NY-REN-11) (Transformation-sensitive protein IEF SSP 3521)
Gene: STIP1

Interactor 2: HSP74 (P34932)
Heat shock 70 kDa protein 4 (HSP70RY) (Heat shock 70-related protein APG-2) (Heat shock protein family H member 2)
Gene: HSPA4

Species: Homo sapiens

Source: intact

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.88	0.60	0.730

Property	Details
Experiments	10642522, 9452498, 33239621, 21235734, 35271311, 11877417
Identification Methods	pull down, affinity chromatography technology, anti tag coimmunoprecipitation
Interaction Type	direct interaction, physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005634 - nucleus GO:0005829 - cytosol
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 543 Hs			1 840
+	Hs
		320819 STIP1_HUMAN (1-543): 2.75e-98: 309: 100.00		HS74L_HUMAN (1-840): 0: 959: 63.21
+	Hs
		684925 STIP1_HUMAN (1-543): 2.75e-98: 309: 100.00		HS105_HUMAN (1-840): 0: 938: 62.95
+	Hs
		714375 DNJC7_HUMAN (209-487): 3.28e-26: 113: 18.28		HSP74_HUMAN (1-840): 0: 993: 100.00
+	Hs
		714418 RPAP3_HUMAN (2-141): 4.46e-20: 96.1: 27.14		HSP74_HUMAN (1-840): 0: 993: 100.00
+	Dm
		1371973 Q9VPN5_DROME (1-542): 1.4e-79: 259: 47.42		Q9VUC1_DROME (1-840): 0: 821: 42.10
+	Hs
		320902 DNJC7_HUMAN (209-487): 3.28e-26: 113: 18.28		HS74L_HUMAN (1-840): 0: 959: 63.21
+	Hs
		1267736 DNJC7_HUMAN (209-487): 3.28e-26: 113: 18.28		HS105_HUMAN (1-840): 0: 938: 62.95
+	Hs
		503534 STIP1_HUMAN (1-543): 2.75e-98: 309: 100.00		HSP7C_HUMAN (564-692): 5.97e-20: 97: 16.92
+	Hs
		483776 STIP1_HUMAN (1-543): 2.75e-98: 309: 100.00		HS71B_HUMAN (571-686): 1.59e-19: 95.5: 23.93
+	Hs
		684439 STIP1_HUMAN (1-543): 2.75e-98: 309: 100.00		HS71L_HUMAN (564-691): 7.22e-19: 93.5: 22.48
+	At
		1338008 HSOP1_ARATH (3-543): 3.3e-98: 310: 41.96		HS704_ARATH (486-691): 1.05e-17: 89.7: 15.57
+	Hs
		564017 STIP1_HUMAN (1-543): 2.75e-98: 309: 100.00		HSP76_HUMAN (587-690): 1.94e-16: 85.8: 22.86
+	Hs
		564151 SGTB_HUMAN (213-348): 5.73e-32: 126: 31.39		HSP76_HUMAN (587-690): 1.94e-16: 85.8: 22.86
+	Hs
		504631 DNJC7_HUMAN (209-487): 3.28e-26: 113: 18.28		HSP7C_HUMAN (564-692): 5.97e-20: 97: 16.92
+	Hs
		483768 DNJC7_HUMAN (209-487): 3.28e-26: 113: 18.28		HS71A_HUMAN (571-686): 1.59e-19: 95.5: 23.93
+	Hs
		483801 DNJC7_HUMAN (209-487): 3.28e-26: 113: 18.28		HS71B_HUMAN (571-686): 1.59e-19: 95.5: 23.93
+	Hs
		1120567 DNJC7_HUMAN (209-487): 3.28e-26: 113: 18.28		Q53FA3_HUMAN (564-691): 3.83e-19: 94.3: 23.26
+	Hs
		714055 DNJC7_HUMAN (209-487): 3.28e-26: 113: 18.28		HS71L_HUMAN (564-691): 7.22e-19: 93.5: 22.48
+	Hs
		564163 DNJC7_HUMAN (209-487): 3.28e-26: 113: 18.28		HSP76_HUMAN (587-690): 1.94e-16: 85.8: 22.86
+	Hs
		564188 RPAP3_HUMAN (2-141): 4.46e-20: 96.1: 27.14		HSP76_HUMAN (587-690): 1.94e-16: 85.8: 22.86