HitPredict

Interactor 1: RUXGL (A8MWD9)
Putative small nuclear ribonucleoprotein G-like protein 15
Gene: SNRPGP15

Interactor 2: DDX23 (Q9BUQ8)
Probable ATP-dependent RNA helicase DDX23 (EC 3.6.4.13) (100 kDa U5 snRNP-specific protein) (DEAD box protein 23) (PRP28 homolog) (U5-100kD)
Gene: DDX23

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.33	0.60	0.445

Property	Details
Experiments	28514442
Identification Methods	anti tag coimmunoprecipitation
Interaction Type	association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0000398 - mRNA splicing, via spliceosome GO:0003723 - RNA binding GO:0005682 - U5 snRNP GO:0071013 - catalytic step 2 spliceosome
Homologous interactions	14

Homologous interactions

Color coding for hit scores

	1 76 Hs			1 820
+	Hs
		912103 RUXG_HUMAN (1-76): 5.34e-30: 102: 94.74		DDX23_HUMAN (1-820): 5.19e-160: 488: 100.00
+	Hs
		912250 LSM6_HUMAN (4-75): 2.84e-27: 95.6: 25.00		DDX23_HUMAN (1-820): 5.19e-160: 488: 100.00
+	Hs
		1313213 LSM7_HUMAN (3-76): 1.31e-24: 89.8: 31.71		DDX23_HUMAN (1-820): 5.19e-160: 488: 100.00
+	Hs
		928011 RSMN_HUMAN (1-70): 9.31e-23: 88.6: 21.25		DDX23_HUMAN (1-820): 5.19e-160: 488: 100.00
+	Hs
		911952 RUXF_HUMAN (5-73): 9.05e-24: 87.1: 26.09		DDX23_HUMAN (1-820): 5.19e-160: 488: 100.00
+	Hs
		539132 RSMB_HUMAN (1-70): 5.01e-22: 86.7: 21.25		DDX23_HUMAN (1-820): 5.19e-160: 488: 100.00
+	Hs
		167714 LSM1_HUMAN (5-74): 1.01e-17: 72.9: 30.14		DDX23_HUMAN (1-820): 5.19e-160: 488: 100.00
+	Hs
		539083 RSMB_HUMAN (1-70): 5.01e-22: 86.7: 21.25		DDX17_HUMAN (337-820): 5.87e-132: 412: 34.97
+	Hs
		133961 RUXF_HUMAN (5-73): 9.05e-24: 87.1: 26.09		DDX3X_HUMAN (236-804): 2.78e-130: 405: 30.65
+	Hs
		571387 RUXF_HUMAN (5-73): 9.05e-24: 87.1: 26.09		DDX5_HUMAN (297-801): 3.08e-129: 401: 32.81
+	Hs
		538830 RSMB_HUMAN (1-70): 5.01e-22: 86.7: 21.25		DDX5_HUMAN (297-801): 3.08e-129: 401: 32.81
+	Sc
		416016 LSM1_YEAST (3-74): 3.52e-22: 85.6: 27.27		DED1_YEAST (348-797): 3.22e-126: 393: 33.55
+	Sc
		415993 RUXG_YEAST (7-76): 5.33e-22: 82.3: 50.69		DED1_YEAST (348-797): 3.22e-126: 393: 33.55
+	Hs
		539176 RSMB_HUMAN (1-70): 5.01e-22: 86.7: 21.25		DDX41_HUMAN (365-795): 7.12e-81: 273: 39.32