HitPredict

Interactor 1: STIP1 (P31948)
Stress-induced-phosphoprotein 1 (STI1) (Hsc70/Hsp90-organizing protein) (Hop) (Renal carcinoma antigen NY-REN-11) (Transformation-sensitive protein IEF SSP 3521)
Gene: STIP1

Interactor 2: PTEN (P60484)
Phosphatidylinositol 3,4,5-trisphosphate 3-phosphatase and dual-specificity protein phosphatase PTEN (EC 3.1.3.16) (EC 3.1.3.48) (EC 3.1.3.67) (Inositol polyphosphate 3-phosphatase) (EC 3.1.3.-) (Mutated in multiple advanced cancers 1) (Phosphatase and tensin homolog)
Gene: PTEN

Species: Homo sapiens

Source: biogrid

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.56	0.60	0.584

Property	Details
Experiments	21532586, 28675297
Identification Methods	affinity chromatography technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005634 - nucleus GO:0005829 - cytosol
Homologous interactions	6

Homologous interactions

Color coding for hit scores

	1 543 Hs			1 403
+	Mm
		139403 STIP1_MOUSE (1-543): 7.88e-97: 306: 97.42		PTEN_MOUSE (1-403): 8.54e-168: 477: 99.75
+	Hs
		684811 STIP1_HUMAN (1-543): 2.75e-98: 309: 100.00		TENS3_HUMAN (17-402): 1.54e-117: 374: 27.46
+	Hs
		684826 STIP1_HUMAN (1-543): 2.75e-98: 309: 100.00		TPTE2_HUMAN (1-347): 4.78e-106: 324: 34.72
+	Hs
		684565 STIP1_HUMAN (1-543): 2.75e-98: 309: 100.00		TPTE_HUMAN (1-347): 1.17e-102: 316: 33.61
+	Hs
		174957 OGT1_HUMAN (5-261): 5.16e-18: 90: 13.57		TENS2_HUMAN (16-402): 1.75e-109: 352: 24.88
+	Hs
		879850 RPAP3_HUMAN (2-141): 4.46e-20: 96.1: 27.14		TPTE_HUMAN (1-347): 1.17e-102: 316: 33.61