HitPredict

Interactor 1: STIP1 (P31948)
Stress-induced-phosphoprotein 1 (STI1) (Hsc70/Hsp90-organizing protein) (Hop) (Renal carcinoma antigen NY-REN-11) (Transformation-sensitive protein IEF SSP 3521)
Gene: STIP1

Interactor 2: FKBP8 (Q14318)
Peptidyl-prolyl cis-trans isomerase FKBP8 (PPIase FKBP8) (EC 5.2.1.8) (38 kDa FK506-binding protein) (38 kDa FKBP) (FKBP-38) (hFKBP38) (FK506-binding protein 8) (FKBP-8) (FKBPR38) (Rotamase)
Gene: FKBP8

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.62	1.00	0.789

Property	Details
Experiments	35271311, 33239621
Identification Methods	affinity chromatography technology, anti tag coimmunoprecipitation
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	TPR_2~TPR_2, TPR_2~TPR_8
Common GO terms	GO:0005829 - cytosol GO:0032991 - protein-containing complex
Homologous interactions	19

Homologous interactions

Color coding for hit scores

	1 543 Hs			1 412
+	Hs
		118697 STIP1_HUMAN (1-543): 2.75e-98: 309: 100.00		AIP_HUMAN (97-369): 4.45e-54: 184: 18.94
+	Hs
		684646 STIP1_HUMAN (1-543): 2.75e-98: 309: 100.00		FKBP4_HUMAN (72-404): 6.45e-24: 105: 18.18
+	Hs
		1053193 RPAP3_HUMAN (2-141): 4.46e-20: 96.1: 27.14		FKBP8_HUMAN (1-412): 5.79e-102: 310: 100.00
+	Hs
		684432 STIP1_HUMAN (1-543): 2.75e-98: 309: 100.00		STIP1_HUMAN (218-357): 3.76e-20: 94.2: 20.00
+	Hs
		174884 OGT1_HUMAN (5-261): 5.16e-18: 90: 13.57		FKBP8_HUMAN (1-412): 5.79e-102: 310: 100.00
+	Hs
		684691 STIP1_HUMAN (1-543): 2.75e-98: 309: 100.00		FKBP5_HUMAN (72-203): 1.44e-18: 89.2: 27.21
+	Dm
		817472 Q9VPN5_DROME (1-542): 1.4e-79: 259: 47.42		FKB12_DROME (107-204): 8.02e-34: 123: 33.33
+	Hs
		1012412 TMTC1_HUMAN (2-318): 1.14e-31: 132: 13.25		Q0VDC6_HUMAN (101-204): 3.56e-34: 125: 32.41
+	Hs
		684975 DNJC7_HUMAN (209-487): 3.28e-26: 113: 18.28		STIP1_HUMAN (218-357): 3.76e-20: 94.2: 20.00
+	Hs
		174814 OGT1_HUMAN (5-261): 5.16e-18: 90: 13.57		FKBP4_HUMAN (72-404): 6.45e-24: 105: 18.18
+	Hs
		685029 RPAP3_HUMAN (2-141): 4.46e-20: 96.1: 27.14		STIP1_HUMAN (218-357): 3.76e-20: 94.2: 20.00
+	Sc
		549696 STI1_YEAST (2-182): 1.26e-14: 78.8: 21.51		STI1_YEAST (221-371): 6.12e-25: 108: 19.21
+	Sc
		422985 TOM70_YEAST (353-515): 2.09e-14: 78: 22.09		STI1_YEAST (221-371): 6.12e-25: 108: 19.21
+	Hs
		1034998 RPAP3_HUMAN (2-141): 4.46e-20: 96.1: 27.14		FKBP5_HUMAN (72-203): 1.44e-18: 89.2: 27.21
+	Hs
		174661 OGT1_HUMAN (5-261): 5.16e-18: 90: 13.57		STIP1_HUMAN (218-357): 3.76e-20: 94.2: 20.00
+	Hs
		174855 OGT1_HUMAN (5-261): 5.16e-18: 90: 13.57		FKBP5_HUMAN (72-203): 1.44e-18: 89.2: 27.21
+	Hs
		972498 IFT88_HUMAN (4-150): 8.37e-09: 60.3: 12.93		FKBP4_HUMAN (72-404): 6.45e-24: 105: 18.18
+	Hs
		297056 TOM70_HUMAN (207-543): 4.08e-13: 73.8: 11.00		FKBP5_HUMAN (72-203): 1.44e-18: 89.2: 27.21
+	Hs
		213490 SGTA_HUMAN (202-327): 3.98e-09: 60.1: 32.54		STIP1_HUMAN (218-357): 3.76e-20: 94.2: 20.00