HitPredict

Interactor 1: STIP1 (P31948)
Stress-induced-phosphoprotein 1 (STI1) (Hsc70/Hsp90-organizing protein) (Hop) (Renal carcinoma antigen NY-REN-11) (Transformation-sensitive protein IEF SSP 3521)
Gene: STIP1

Interactor 2: HS904 (Q58FG1)
Putative heat shock protein HSP 90-alpha A4 (Heat shock 90 kDa protein 1 alpha-like 2) (Heat shock protein 90-alpha D) (Heat shock protein 90Ad)
Gene: HSP90AA4P

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.50	1.00	0.712

Property	Details
Experiments	28514442, 33961781
Identification Methods	anti tag coimmunoprecipitation
Interaction Type	association

Property	Details
Interacting Pfam domains	HSP90~TPR_8
Common GO terms	GO:0005634 - nucleus GO:0005829 - cytosol GO:0032991 - protein-containing complex
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 543 Hs			1 418
+	Hs
		684789 STIP1_HUMAN (1-543): 2.75e-98: 309: 100.00		H90B2_HUMAN (2-304): 8.06e-80: 252: 34.81
+	Hs
		684788 STIP1_HUMAN (1-543): 2.75e-98: 309: 100.00		H90B3_HUMAN (2-153): 1.55e-48: 175: 50.66
+	Hs
		111934 STIP1_HUMAN (1-543): 2.75e-98: 309: 100.00		K9JA46_HUMAN (96-271): 2.07e-45: 169: 51.41
+	Hs
		431574 STIP1_HUMAN (1-543): 2.75e-98: 309: 100.00		HS90A_HUMAN (96-271): 2.07e-45: 169: 51.41
+	At
		878278 HSOP2_ARATH (3-543): 4.73e-97: 307: 41.86		HS902_ARATH (96-256): 1.44e-42: 160: 49.08
+	Hs
		437930 STIP1_HUMAN (1-543): 2.75e-98: 309: 100.00		HS90B_HUMAN (96-256): 4.57e-41: 156: 51.85
+	Hs
		538123 STIP1_HUMAN (1-543): 2.75e-98: 309: 100.00		ENPL_HUMAN (96-407): 1.36e-36: 144: 26.90
+	Hs
		684849 STIP1_HUMAN (1-543): 2.75e-98: 309: 100.00		Q86SX1_HUMAN (2-80): 1.57e-39: 144: 91.14
+	Dm
		365481 Q9VPN5_DROME (1-542): 1.4e-79: 259: 47.42		HSP83_DROME (96-256): 2.48e-43: 162: 52.15
+	Hs
		684787 STIP1_HUMAN (1-543): 2.75e-98: 309: 100.00		H90B4_HUMAN (112-275): 1.78e-26: 112: 42.42
+	Hs
		1123473 DNJC7_HUMAN (209-487): 3.28e-26: 113: 18.28		H90B2_HUMAN (2-304): 8.06e-80: 252: 34.81
+	Hs
		432195 DNJC7_HUMAN (209-487): 3.28e-26: 113: 18.28		HS90A_HUMAN (96-271): 2.07e-45: 169: 51.41
+	Hs
		538353 SGTB_HUMAN (213-348): 5.73e-32: 126: 31.39		ENPL_HUMAN (96-407): 1.36e-36: 144: 26.90
+	Hs
		438464 DNJC7_HUMAN (209-487): 3.28e-26: 113: 18.28		HS90B_HUMAN (96-256): 4.57e-41: 156: 51.85
+	Sc
		366262 TOM71_YEAST (71-537): 1.63e-23: 106: 12.25		HSP82_YEAST (111-258): 1.18e-42: 160: 46.62
+	Sc
		543696 TOM71_YEAST (71-537): 1.63e-23: 106: 12.25		HSC82_YEAST (111-258): 2.14e-42: 160: 46.62
+	Hs
		432268 RPAP3_HUMAN (2-141): 4.46e-20: 96.1: 27.14		HS90A_HUMAN (96-271): 2.07e-45: 169: 51.41
+	Hs
		174556 OGT1_HUMAN (5-261): 5.16e-18: 90: 13.57		HS90A_HUMAN (96-271): 2.07e-45: 169: 51.41
+	Hs
		438533 RPAP3_HUMAN (2-141): 4.46e-20: 96.1: 27.14		HS90B_HUMAN (96-256): 4.57e-41: 156: 51.85
+	Hs
		1162526 RPAP3_HUMAN (2-141): 4.46e-20: 96.1: 27.14		Q6PK50_HUMAN (96-157): 2.21e-13: 72.7: 61.91