HitPredict

Interactor 1: STIP1 (P31948)
Stress-induced-phosphoprotein 1 (STI1) (Hsc70/Hsp90-organizing protein) (Hop) (Renal carcinoma antigen NY-REN-11) (Transformation-sensitive protein IEF SSP 3521)
Gene: STIP1

Interactor 2: LRRK2 (Q5S007)
Leucine-rich repeat serine/threonine-protein kinase 2 (EC 2.7.11.1) (EC 3.6.5.-) (Dardarin)
Gene: LRRK2

Species: Homo sapiens

Source: intact

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.62	0.60	0.611

Property	Details
Experiments	24510904, 31046837
Identification Methods	pull down, affinity chromatography technology, protein array
Interaction Type	direct interaction, physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005794 - Golgi apparatus GO:0005829 - cytosol
Homologous interactions	8

Homologous interactions

Color coding for hit scores

	1 543 Hs			1 2527
+	Hs
		66551 A8K690_HUMAN (1-543): 2.02e-96: 305: 99.82		LRRK2_HUMAN (1-2527): 0: 3008: 99.72
+	Hs
		1130486 DNJC7_HUMAN (209-487): 3.28e-26: 113: 18.28		LRRK2_HUMAN (1-2527): 0: 3008: 99.72
+	Hs
		1130595 RPAP3_HUMAN (2-141): 4.46e-20: 96.1: 27.14		LRRK2_HUMAN (1-2527): 0: 3008: 99.72
+	Hs
		174950 OGT1_HUMAN (5-261): 5.16e-18: 90: 13.57		LRRK2_HUMAN (1-2527): 0: 3008: 99.72
+	Hs
		297066 TOM70_HUMAN (207-543): 4.08e-13: 73.8: 11.00		LRRK2_HUMAN (1-2527): 0: 3008: 99.72
+	Hs
		684476 STIP1_HUMAN (1-543): 2.75e-98: 309: 100.00		CSK_HUMAN (1722-2140): 2.25e-102: 339: 20.74
+	Hs
		175307 OGT1_HUMAN (5-261): 5.16e-18: 90: 13.57		SHOC2_HUMAN (944-1353): 1.23e-60: 222: 22.27
+	Hs
		1332525 RPAP3_HUMAN (2-141): 4.46e-20: 96.1: 27.14		MFHA1_HUMAN (838-1119): 1.5e-30: 134: 16.95