HitPredict

Interactor 1: COPG (P32074)
Coatomer subunit gamma (Gamma-coat protein) (Gamma-COP)
Gene: SEC21

Interactor 2: GEA1 (P47102)
ARF guanine-nucleotide exchange factor 1
Gene: GEA1

Species: Saccharomyces cerevisiae S288C

Source: mint

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.68	0.60	0.639

Property	Details
Experiments	33401608, 19039328
Identification Methods	affinity chromatography technology, two hybrid, pull down, anti tag coimmunoprecipitation
Interaction Type	physical association, direct interaction

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005783 - endoplasmic reticulum GO:0006888 - endoplasmic reticulum to Golgi vesicle-mediated transport GO:0006890 - retrograde vesicle-mediated transport, Golgi to endoplasmic reticulum GO:0006891 - intra-Golgi vesicle-mediated transport
Homologous interactions	8

Homologous interactions

Color coding for hit scores

	1 935 Sc			1 1408
+	Sc
		685530 COPG_YEAST (1-935): 0: 598: 100.00		GEA2_YEAST (10-1407): 0: 1167: 50.74
+	Sc
		502964 COPG_YEAST (1-935): 0: 598: 100.00		SEC7_YEAST (31-1379): 0: 767: 14.18
+	Hs
		1348510 COPG2_HUMAN (7-933): 0: 666: 32.34		PSD3_HUMAN (461-798): 5.88e-73: 267: 19.60
+	Hs
		1348516 COPG1_HUMAN (3-933): 0: 655: 31.71		PSD3_HUMAN (461-798): 5.88e-73: 267: 19.60
+	Hs
		1266585 COPG2_HUMAN (7-933): 0: 666: 32.34		GBF1_HUMAN (1240-1386): 2.75e-25: 116: 20.51
+	Hs
		863351 COPB_HUMAN (14-926): 2.26e-167: 515: 10.07		PSD3_HUMAN (461-798): 5.88e-73: 267: 19.60
+	Hs
		1266622 COPG1_HUMAN (3-933): 0: 655: 31.71		GBF1_HUMAN (1240-1386): 2.75e-25: 116: 20.51
+	Hs
		863280 COPB_HUMAN (14-926): 2.26e-167: 515: 10.07		GBF1_HUMAN (1240-1386): 2.75e-25: 116: 20.51