HitPredict

Interactor 1: PRDX2 (P32119)
Peroxiredoxin-2 (EC 1.11.1.24) (Natural killer cell-enhancing factor B) (NKEF-B) (PRP) (Thiol-specific antioxidant protein) (TSA) (Thioredoxin peroxidase 1) (Thioredoxin-dependent peroxide reductase 1) (Thioredoxin-dependent peroxiredoxin 2)
Gene: PRDX2

Interactor 2: CDK9 (P50750)
Cyclin-dependent kinase 9 (EC 2.7.11.22) (EC 2.7.11.23) (C-2K) (Cell division cycle 2-like protein kinase 4) (Cell division protein kinase 9) (Serine/threonine-protein kinase PITALRE) (Tat-associated kinase complex catalytic subunit)
Gene: CDK9

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.38	0.50	0.437

Property	Details
Experiments	27684187
Identification Methods	affinity chromatography technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	-
Homologous interactions	10

Homologous interactions

Color coding for hit scores

	1 198 Hs			1 372
+	Hs
		841674 PRDX1_HUMAN (1-197): 7.49e-100: 288: 77.78		CDK9_HUMAN (1-372): 2.88e-147: 422: 100.00
+	Hs
		625163 PRDX2_HUMAN (1-198): 3.46e-104: 299: 100.00		CDK2_HUMAN (16-321): 4.46e-136: 391: 38.76
+	Hs
		625149 PRDX3_HUMAN (2-198): 8.33e-101: 293: 63.45		CDK2_HUMAN (16-321): 4.46e-136: 391: 38.76
+	Hs
		625384 PRDX1_HUMAN (1-197): 7.49e-100: 288: 77.78		CDK2_HUMAN (16-321): 4.46e-136: 391: 38.76
+	Hs
		647478 PRDX3_HUMAN (2-198): 8.33e-101: 293: 63.45		MK03_HUMAN (1-359): 1.92e-131: 382: 30.36
+	Rn
		600501 PRDX3_RAT (2-198): 7.04e-98: 286: 63.45		MK03_RAT (9-362): 2.63e-130: 379: 30.79
+	Hs
		414776 PRDX2_HUMAN (1-198): 3.46e-104: 299: 100.00		CDK1_HUMAN (16-315): 5.07e-124: 361: 40.40
+	Hs
		414885 PRDX1_HUMAN (1-197): 7.49e-100: 288: 77.78		CDK1_HUMAN (16-315): 5.07e-124: 361: 40.40
+	Hs
		625148 PRDX6_HUMAN (4-196): 1.88e-67: 207: 29.13		CDK2_HUMAN (16-321): 4.46e-136: 391: 38.76
+	Hs
		658802 PRDX6_HUMAN (4-196): 1.88e-67: 207: 29.13		MK01_HUMAN (5-359): 1.35e-131: 382: 30.99