HitPredict

Interactor 1: PRDX2 (P32119)
Peroxiredoxin-2 (EC 1.11.1.24) (Natural killer cell-enhancing factor B) (NKEF-B) (PRP) (Thiol-specific antioxidant protein) (TSA) (Thioredoxin peroxidase 1) (Thioredoxin-dependent peroxide reductase 1) (Thioredoxin-dependent peroxiredoxin 2)
Gene: PRDX2

Interactor 2: NEK2 (P51955)
Serine/threonine-protein kinase Nek2 (EC 2.7.11.1) (HSPK 21) (Never in mitosis A-related kinase 2) (NimA-related protein kinase 2) (NimA-like protein kinase 1)
Gene: NEK2

Species: Homo sapiens

Source: biogrid

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.38	0.60	0.479

Property	Details
Experiments	29863498
Identification Methods	affinity chromatography technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005737 - cytoplasm GO:0005829 - cytosol
Homologous interactions	9

Homologous interactions

Color coding for hit scores

	1 198 Hs			1 445
+	Hs
		670971 PRDX3_HUMAN (2-198): 8.33e-101: 293: 63.45		MARK2_HUMAN (2-425): 7.56e-123: 377: 23.56
+	Rn
		727698 PRDX2_RAT (1-198): 6.46e-104: 299: 93.43		AAPK1_RAT (4-383): 1.2e-108: 333: 27.32
+	Hs
		685674 PRDX2_HUMAN (1-198): 3.46e-104: 299: 100.00		STK4_HUMAN (6-442): 1.98e-108: 330: 22.75
+	Rn
		871298 PRDX1_RAT (1-197): 3.67e-100: 289: 77.78		AAPK1_RAT (4-383): 1.2e-108: 333: 27.32
+	Hs
		989275 PRDX1_HUMAN (1-197): 7.49e-100: 288: 77.78		STK4_HUMAN (6-442): 1.98e-108: 330: 22.75
+	Hs
		851466 PRDX1_HUMAN (1-197): 7.49e-100: 288: 77.78		NEK4_HUMAN (8-271): 2.82e-49: 181: 40.91
+	Hs
		671025 PRDX3_HUMAN (2-198): 8.33e-101: 293: 63.45		NEK6_HUMAN (7-262): 2.56e-50: 174: 37.69
+	Hs
		989329 PRDX1_HUMAN (1-197): 7.49e-100: 288: 77.78		NEK10_HUMAN (7-275): 5.22e-37: 146: 32.98
+	Hs
		670741 PRDX6_HUMAN (4-196): 1.88e-67: 207: 29.13		NEK7_HUMAN (7-267): 1.49e-47: 167: 35.85