HitPredict

Interactor 1: PRDX2 (P32119)
Peroxiredoxin-2 (EC 1.11.1.24) (Natural killer cell-enhancing factor B) (NKEF-B) (PRP) (Thiol-specific antioxidant protein) (TSA) (Thioredoxin peroxidase 1) (Thioredoxin-dependent peroxide reductase 1) (Thioredoxin-dependent peroxiredoxin 2)
Gene: PRDX2

Interactor 2: COP1 (Q8NHY2)
E3 ubiquitin-protein ligase COP1 (EC 2.3.2.27) (Constitutive photomorphogenesis protein 1 homolog) (hCOP1) (RING finger and WD repeat domain protein 2) (RING finger protein 200) (RING-type E3 ubiquitin transferase RFWD2)
Gene: COP1

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.38	0.60	0.479

Property	Details
Experiments	37689310
Identification Methods	proximity labelling technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005829 - cytosol
Homologous interactions	10

Homologous interactions

Color coding for hit scores

	1 198 Hs			1 731
+	Sc
		713213 TSA1_YEAST (6-198): 1.78e-89: 262: 66.84		TAF5_YEAST (96-683): 1.17e-82: 280: 14.26
+	Hs
		670992 PRDX3_HUMAN (2-198): 8.33e-101: 293: 63.45		FBXW7_HUMAN (452-730): 4.46e-69: 242: 17.15
+	Hs
		1026714 PRDX4_HUMAN (5-198): 2.62e-96: 282: 70.10		WDR5B_HUMAN (336-625): 1.65e-63: 216: 17.79
+	Mm
		139713 PRDX6_MOUSE (4-196): 5.15e-72: 219: 29.13		FBXW7_MOUSE (452-730): 4.71e-69: 242: 17.15
+	Hs
		685670 PRDX2_HUMAN (1-198): 3.46e-104: 299: 100.00		RBBP4_HUMAN (512-702): 3.22e-20: 96: 14.49
+	Hs
		685697 PRDX2_HUMAN (1-198): 3.46e-104: 299: 100.00		RBBP7_HUMAN (476-629): 3.89e-12: 70.9: 29.34
+	Hs
		903161 PRDX1_HUMAN (1-197): 7.49e-100: 288: 77.78		WDR5_HUMAN (632-730): 5.38e-16: 81.8: 18.18
+	Hs
		1026733 PRDX4_HUMAN (5-198): 2.62e-96: 282: 70.10		POC1B_HUMAN (627-728): 3.91e-13: 74.5: 18.63
+	Ce
		953990 TDX1_CAEEL (1-198): 2.16e-92: 271: 59.09		LIN53_CAEEL (552-730): 5.7e-14: 76.7: 16.75
+	Hs
		670686 PRDX6_HUMAN (4-196): 1.88e-67: 207: 29.13		WDR5_HUMAN (632-730): 5.38e-16: 81.8: 18.18