HitPredict

Interactor 1: PRDX2 (P32119)
Peroxiredoxin-2 (EC 1.11.1.24) (Natural killer cell-enhancing factor B) (NKEF-B) (PRP) (Thiol-specific antioxidant protein) (TSA) (Thioredoxin peroxidase 1) (Thioredoxin-dependent peroxide reductase 1) (Thioredoxin-dependent peroxiredoxin 2)
Gene: PRDX2

Interactor 2: M4K5 (Q9Y4K4)
Mitogen-activated protein kinase kinase kinase kinase 5 (EC 2.7.11.1) (Kinase homologous to SPS1/STE20) (KHS) (MAPK/ERK kinase kinase kinase 5) (MEK kinase kinase 5) (MEKKK 5)
Gene: MAP4K5

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.38	0.60	0.479

Property	Details
Experiments	32640226
Identification Methods	affinity chromatography technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005737 - cytoplasm GO:0005829 - cytosol
Homologous interactions	5

Homologous interactions

Color coding for hit scores

	1 198 Hs			1 846
+	Hs
		1018150 PRDX4_HUMAN (5-198): 2.62e-96: 282: 70.10		M4K2_HUMAN (9-846): 0: 833: 50.30
+	Hs
		670971 PRDX3_HUMAN (2-198): 8.33e-101: 293: 63.45		MARK2_HUMAN (2-473): 3.58e-124: 394: 21.36
+	Hs
		685674 PRDX2_HUMAN (1-198): 3.46e-104: 299: 100.00		STK4_HUMAN (10-278): 1.36e-120: 375: 45.93
+	Hs
		989275 PRDX1_HUMAN (1-197): 7.49e-100: 288: 77.78		STK4_HUMAN (10-278): 1.36e-120: 375: 45.93
+	Hs
		989278 PRDX1_HUMAN (1-197): 7.49e-100: 288: 77.78		STK3_HUMAN (1-408): 2.41e-120: 374: 32.45