HitPredict

Interactor 1: ARRB2 (P32121)
Beta-arrestin-2 (Arrestin beta-2) (Non-visual arrestin-3)
Gene: ARRB2

Interactor 2: OPRD (P41143)
Delta-type opioid receptor (D-OR-1) (DOR-1)
Gene: OPRD1

Species: Homo sapiens

Source: biogrid

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.58	1.00	0.768

Property	Details
Experiments	11259507, 28388416
Identification Methods	pull down, proximity labelling technology
Interaction Type	direct interaction, physical association

Property	Details
Interacting Pfam domains	7tm_1~Arrestin_C, 7tm_1~Arrestin_N
Common GO terms	GO:0005886 - plasma membrane
Homologous interactions	12

Homologous interactions

Color coding for hit scores

	1 409 Hs			1 372
+	Hs
		781016 ARRB1_HUMAN (1-407): 0: 661: 76.15		OPRD_HUMAN (1-372): 3.55e-101: 305: 100.00
+	Hs
		428933 ARRB2_HUMAN (1-409): 0: 688: 100.00		ADRB2_HUMAN (29-339): 2.14e-77: 245: 22.12
+	Hs
		441648 ARRB2_HUMAN (1-409): 0: 688: 100.00		ADRB1_HUMAN (1-354): 2.29e-74: 240: 18.78
+	Rn
		663954 ARRB2_RAT (1-409): 0: 682: 95.85		Q8VBU7_RAT (45-363): 7.93e-77: 244: 21.90
+	Hs
		685813 ARRB2_HUMAN (1-409): 0: 688: 100.00		APJ_HUMAN (51-367): 3.24e-72: 231: 27.88
+	Hs
		674827 ARRB2_HUMAN (1-409): 0: 688: 100.00		AGTR1_HUMAN (38-369): 3.77e-72: 230: 28.74
+	Hs
		827128 ARRB1_HUMAN (1-407): 0: 661: 76.15		CCR5_HUMAN (35-365): 2.36e-81: 254: 23.44
+	Rn
		626614 ARRB2_RAT (1-409): 0: 682: 95.85		AGTRA_RAT (38-369): 1.51e-72: 231: 28.45
+	Hs
		441649 ARRB1_HUMAN (1-407): 0: 661: 76.15		ADRB1_HUMAN (1-354): 2.29e-74: 240: 18.78
+	Hs
		674834 ARRB1_HUMAN (1-407): 0: 661: 76.15		AGTR1_HUMAN (38-369): 3.77e-72: 230: 28.74
+	Rn
		626613 ARRB1_RAT (1-399): 0: 654: 76.90		AGTRA_RAT (38-369): 1.51e-72: 231: 28.45
+	Mm
		669680 ARRB1_MOUSE (1-399): 0: 652: 76.90		AGTRA_MOUSE (38-371): 3.9e-72: 230: 28.28