HitPredict

Interactor 1: OTX1 (P32242)
Homeobox protein OTX1 (Orthodenticle homolog 1)
Gene: OTX1

Interactor 2: KRA42 (Q9BYR5)
Keratin-associated protein 4-2 (Keratin-associated protein 4.2) (Ultrahigh sulfur keratin-associated protein 4.2)
Gene: KRTAP4-2

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.66	0.50	0.578

Property	Details
Experiments	25416956, 36949045
Identification Methods	two hybrid, two hybrid prey pooling approach, two hybrid array, validated two hybrid
Interaction Type	direct interaction, physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	-
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 354 Hs			1 136
+	Hs
		686509 OTX1_HUMAN (1-354): 6.35e-58: 193: 100.00		KR412_HUMAN (2-136): 5.17e-26: 98.6: 64.38
+	Hs
		686416 OTX1_HUMAN (1-354): 6.35e-58: 193: 100.00		KR122_HUMAN (1-135): 9.56e-23: 88.5: 33.82
+	Hs
		686492 OTX1_HUMAN (1-354): 6.35e-58: 193: 100.00		KRA13_HUMAN (3-135): 4.44e-22: 87.4: 34.57
+	Hs
		686490 OTX1_HUMAN (1-354): 6.35e-58: 193: 100.00		KR111_HUMAN (1-134): 7.05e-20: 81.6: 28.36
+	Hs
		686418 OTX1_HUMAN (1-354): 6.35e-58: 193: 100.00		KR124_HUMAN (1-104): 6.42e-19: 77.8: 35.58
+	Hs
		686421 OTX1_HUMAN (1-354): 6.35e-58: 193: 100.00		KR105_HUMAN (26-135): 1.38e-16: 75.4: 36.80
+	Hs
		686420 OTX1_HUMAN (1-354): 6.35e-58: 193: 100.00		KR103_HUMAN (35-136): 1.08e-16: 74.7: 36.36
+	Hs
		686513 OTX1_HUMAN (1-354): 6.35e-58: 193: 100.00		KRA93_HUMAN (29-134): 6.33e-17: 73.9: 42.73
+	Hs
		686422 OTX1_HUMAN (1-354): 6.35e-58: 193: 100.00		KR107_HUMAN (16-136): 3.47e-14: 69.7: 29.63
+	Hs
		686423 OTX1_HUMAN (1-354): 6.35e-58: 193: 100.00		KR108_HUMAN (14-136): 9.72e-14: 67.4: 27.48
+	Hs
		686424 OTX1_HUMAN (1-354): 6.35e-58: 193: 100.00		KR109_HUMAN (4-116): 3e-13: 66.6: 30.53
+	Hs
		686514 OTX1_HUMAN (1-354): 6.35e-58: 193: 100.00		KRA92_HUMAN (33-134): 1.36e-13: 65.8: 43.20
+	Hs
		686512 OTX1_HUMAN (1-354): 6.35e-58: 193: 100.00		KRA94_HUMAN (34-136): 8.37e-13: 63.1: 42.72
+	Hs
		686425 OTX1_HUMAN (1-354): 6.35e-58: 193: 100.00		KR10B_HUMAN (2-116): 1.77e-11: 61.6: 32.52
+	Hs
		686419 OTX1_HUMAN (1-354): 6.35e-58: 193: 100.00		KR101_HUMAN (51-135): 9.54e-11: 59.3: 35.48
+	Hs
		686511 OTX1_HUMAN (1-354): 6.35e-58: 193: 100.00		KRA98_HUMAN (43-124): 2.53e-11: 59.3: 45.35
+	Hs
		473266 OTX1_HUMAN (1-354): 6.35e-58: 193: 100.00		KRA23_HUMAN (19-135): 7.72e-11: 57.3: 31.20
+	Hs
		686417 OTX1_HUMAN (1-354): 6.35e-58: 193: 100.00		KR123_HUMAN (51-136): 9.22e-11: 56.6: 33.33
+	Hs
		686434 OTX1_HUMAN (1-354): 6.35e-58: 193: 100.00		KRA11_HUMAN (3-124): 1.33e-09: 55: 24.81
+	Hs
		686415 OTX1_HUMAN (1-354): 6.35e-58: 193: 100.00		KR121_HUMAN (3-87): 5.9e-09: 51.6: 27.06