Interactor 1: ACHA3 (P32297)
Neuronal acetylcholine receptor subunit alpha-3
Gene: CHRNA3

Interactor 2: 5HT3A (P46098)
5-hydroxytryptamine receptor 3A (5-HT3-A) (5-HT3A) (5-hydroxytryptamine receptor 3) (5-HT-3) (5-HT3R) (Serotonin receptor 3A) (Serotonin-gated ion channel receptor)
Gene: HTR3A

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score Annotation score Interaction score
0.65 1.00 0.811

The method score is based on:

Property Details
Experiments 28514442, 33961781
Identification Methods affinity chromatography technology, anti tag coimmunoprecipitation
Interaction Type physical association, association

The annotation score is based on:

Property Details
Interacting Pfam domains Neur_chan_LBD~Neur_chan_LBD, Neur_chan_LBD~Neur_chan_memb, Neur_chan_memb~Neur_chan_memb
Common GO terms GO:0005886 - plasma membrane
GO:0022848 - acetylcholine-gated monoatomic cation-selective channel activity
GO:0043005 - neuron projection
GO:0045202 - synapse
GO:0045211 - postsynaptic membrane
Homologous interactions 18

Homologous interactions

Color coding for hit scores

1 505
Hs

1 478
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Service provided by Combinatics, Japan

Last updated: 15 Jul 2024