HitPredict

Interactor 1: ACHA3 (P32297)
Neuronal acetylcholine receptor subunit alpha-3
Gene: CHRNA3

Interactor 2: EDA (Q92838)
Ectodysplasin-A (Ectodermal dysplasia protein) (EDA protein) [Cleaved into: Ectodysplasin-A, membrane form; Ectodysplasin-A, secreted form]
Gene: EDA

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.65	0.60	0.628

Property	Details
Experiments	28514442, 33961781
Identification Methods	affinity chromatography technology, anti tag coimmunoprecipitation
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005886 - plasma membrane GO:0016020 - membrane
Homologous interactions	4

Homologous interactions

Color coding for hit scores

	1 505 Hs			1 391
+	Hs
		677159 ACHB4_HUMAN (15-505): 0: 526: 45.25		EDA_HUMAN (235-391): 7.4e-58: 195: 100.00
+	Hs
		989638 ACHD_HUMAN (28-502): 3.45e-162: 471: 37.14		EDA_HUMAN (235-391): 7.4e-58: 195: 100.00
+	Hs
		506340 ACHB_HUMAN (25-501): 1.12e-157: 459: 36.20		EDA_HUMAN (235-391): 7.4e-58: 195: 100.00
+	Hs
		798549 ACHA4_HUMAN (366-502): 3.88e-24: 108: 32.12		EDA_HUMAN (235-391): 7.4e-58: 195: 100.00