HitPredict

Interactor 1: VPS10 (P32319)
Vacuolar protein sorting/targeting protein VPS10 (Carboxypeptidase Y receptor) (CPY receptor) (Carboxypeptidase Y-deficient protein 1) (Sortilin VPS10) (Vacuolar carboxypeptidase sorting receptor VPS10) (Vacuolar protein sorting-associated protein 10) (Vacuolar protein-targeting protein 1)
Gene: PEP1

Interactor 2: VPS10 (P32319)
Vacuolar protein sorting/targeting protein VPS10 (Carboxypeptidase Y receptor) (CPY receptor) (Carboxypeptidase Y-deficient protein 1) (Sortilin VPS10) (Vacuolar carboxypeptidase sorting receptor VPS10) (Vacuolar protein sorting-associated protein 10) (Vacuolar protein-targeting protein 1)
Gene: PEP1

Species: Saccharomyces cerevisiae S288C

Source: mint

Category: High-throughput

Confidence: High

Method score Annotation score Interaction score
0.65 1.00 0.811

The method score is based on:

Property Details
Experiments 18467557, 14759368
Identification Methods protein complementation assay, affinity chromatography technology, dihydrofolate reductase reconstruction, anti tag coimmunoprecipitation
Interaction Type direct interaction, physical association

The annotation score is based on:

Property Details
Interacting Pfam domains Sortilin-Vps10~Sortilin-Vps10, Sortilin_C~Sortilin-Vps10
Common GO terms GO:0000166 - nucleotide binding
GO:0000324 - fungal-type vacuole
GO:0000423 - mitophagy
GO:0000425 - pexophagy
GO:0005048 - signal sequence binding
and 8 others

more...
Homologous interactions 4

Homologous interactions

Color coding for hit scores

1 1579
Sc

1 1579
+ Hs
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Last updated: 15 Jul 2024