HitPredict

Interactor 1: PTBP1 (P26599)
Polypyrimidine tract-binding protein 1 (PTB) (57 kDa RNA-binding protein PPTB-1) (Heterogeneous nuclear ribonucleoprotein I) (hnRNP I)
Gene: PTBP1

Interactor 2: GRB7 (Q14451)
Growth factor receptor-bound protein 7 (B47) (Epidermal growth factor receptor GRB-7) (GRB7 adapter protein)
Gene: GRB7

Species: Homo sapiens

Source: biogrid

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.38	0.60	0.479

Property	Details
Experiments	32360748
Identification Methods	affinity chromatography technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0003723 - RNA binding
Homologous interactions	7

Homologous interactions

Color coding for hit scores

	1 557 Hs			1 532
+	Rn
		1424309 PABP1_RAT (3-375): 2.42e-45: 171: 13.58		GRB7_RAT (1-532): 0: 606: 90.30
+	Hs
		440381 PTBP1_HUMAN (1-557): 1.59e-121: 370: 100.00		FYN_HUMAN (357-529): 2.68e-50: 182: 20.88
+	Hs
		687376 PTBP1_HUMAN (1-557): 1.59e-121: 370: 100.00		GRB2_HUMAN (427-513): 2.67e-13: 71: 29.89
+	Hs
		550100 PABP1_HUMAN (3-375): 2.22e-45: 171: 13.58		SRC_HUMAN (351-528): 1.08e-46: 172: 24.32
+	Hs
		557468 PABP3_HUMAN (3-375): 6.42e-45: 170: 13.42		SRC_HUMAN (351-528): 1.08e-46: 172: 24.32
+	Hs
		557280 PABP4_HUMAN (3-378): 2.7e-44: 168: 10.62		SRC_HUMAN (351-528): 1.08e-46: 172: 24.32
+	Hs
		550216 PABP1_HUMAN (3-375): 2.22e-45: 171: 13.58		GRB2_HUMAN (427-513): 2.67e-13: 71: 29.89