HitPredict

Interactor 1: PYC2 (P32327)
Pyruvate carboxylase 2 (EC 6.4.1.1) (Pyruvic carboxylase 2) (PCB 2)
Gene: PYC2

Interactor 2: HSP7F (P32589)
Heat shock protein homolog SSE1 (Chaperone protein MSI3)
Gene: SSE1

Species: Saccharomyces cerevisiae S288C

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.33	0.60	0.445

Property	Details
Experiments	19536198
Identification Methods	tandem affinity purification
Interaction Type	association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005524 - ATP binding GO:0005737 - cytoplasm GO:0005829 - cytosol
Homologous interactions	19

Homologous interactions

Color coding for hit scores

	1 1180 Sc			1 693
+	Hs
		503328 PYC_HUMAN (2-1170): 0: 1368: 52.90		HSP7C_HUMAN (2-645): 0: 851: 27.04
+	Hs
		513537 PYC_HUMAN (2-1170): 0: 1368: 52.90		HSP74_HUMAN (6-650): 5.45e-136: 421: 38.47
+	Sc
		493420 PYC2_YEAST (1-1180): 0: 1489: 100.00		HSP72_YEAST (1-382): 1.15e-71: 246: 36.82
+	Sc
		490602 PYC2_YEAST (1-1180): 0: 1489: 100.00		HSP71_YEAST (1-382): 7.01e-71: 244: 36.55
+	Sc
		493024 PYC1_YEAST (3-1179): 0: 1471: 92.86		HSP72_YEAST (1-382): 1.15e-71: 246: 36.82
+	Sc
		695926 HFA1_YEAST (10-589): 4.16e-146: 489: 25.69		HSP79_YEAST (1-677): 0: 992: 77.11
+	Hs
		503999 ACACA_HUMAN (3-589): 9.01e-159: 525: 26.48		HSP7C_HUMAN (2-645): 0: 851: 27.04
+	Sc
		692656 DUR1_YEAST (6-472): 5.73e-150: 495: 37.19		HSP7F_YEAST (1-693): 0: 829: 100.00
+	Sc
		694368 HFA1_YEAST (10-589): 4.16e-146: 489: 25.69		HSP7F_YEAST (1-693): 0: 829: 100.00
+	Sc
		695313 ACAC_YEAST (5-589): 7.97e-141: 473: 26.20		HSP7F_YEAST (1-693): 0: 829: 100.00
+	Hs
		503486 PYR1_HUMAN (23-428): 3.04e-52: 204: 13.64		HSP7C_HUMAN (2-645): 0: 851: 27.04
+	Hs
		504611 MCCA_HUMAN (954-1173): 1.24e-53: 203: 20.16		HSP7C_HUMAN (2-645): 0: 851: 27.04
+	Hs
		398218 PCCA_HUMAN (955-1170): 9.93e-51: 194: 17.95		HSP7C_HUMAN (2-645): 0: 851: 27.04
+	Sc
		449983 HFA1_YEAST (10-589): 4.16e-146: 489: 25.69		HSP73_YEAST (1-642): 5.45e-72: 247: 28.33
+	Sc
		493536 HFA1_YEAST (10-589): 4.16e-146: 489: 25.69		HSP72_YEAST (1-382): 1.15e-71: 246: 36.82
+	Sc
		490734 HFA1_YEAST (10-589): 4.16e-146: 489: 25.69		HSP71_YEAST (1-382): 7.01e-71: 244: 36.55
+	Sc
		494719 ACAC_YEAST (5-589): 7.97e-141: 473: 26.20		HSP72_YEAST (1-382): 1.15e-71: 246: 36.82
+	Sc
		492143 ACAC_YEAST (5-589): 7.97e-141: 473: 26.20		HSP71_YEAST (1-382): 7.01e-71: 244: 36.55
+	Sc
		372788 CARB_YEAST (24-556): 2.51e-44: 177: 13.83		HSP72_YEAST (1-382): 1.15e-71: 246: 36.82