HitPredict

Interactor 1: IMB3 (P32337)
Importin subunit beta-3 (Karyopherin subunit beta-3) (Karyopherin-121) (Protein secretion enhancer 1)
Gene: PSE1

Interactor 2: NU145 (P49687)
Nucleoporin NUP145 (EC 3.4.21.-) (Nuclear pore protein NUP145) [Cleaved into: Nucleoporin NUP145N (N-NUP145); Nucleoporin NUP145C (C-NUP145)]
Gene: NUP145

Species: Saccharomyces cerevisiae S288C

Source: biogrid

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.70	0.60	0.651

Property	Details
Experiments	9864357, 10678175, 22357553
Identification Methods	filter binding, fluorescent resonance energy transfer, pull down
Interaction Type	physical association, direct interaction

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0006606 - protein import into nucleus GO:0008139 - nuclear localization sequence binding
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 1089 Sc			1 1317
+	Sc
		687986 IMB3_YEAST (1-1089): 3.51e-179: 555: 100.00		NU100_YEAST (45-542): 1.84e-14: 80.8: 14.10
+	Sc
		541851 IMB3_YEAST (1-1089): 3.51e-179: 555: 100.00		NSP1_YEAST (3-459): 5.33e-11: 69.3: 13.35
+	Sc
		687967 IMB3_YEAST (1-1089): 3.51e-179: 555: 100.00		NUP57_YEAST (118-368): 1.26e-10: 67.7: 15.33
+	Sc
		687987 IMB3_YEAST (1-1089): 3.51e-179: 555: 100.00		NU116_YEAST (43-484): 6.18e-10: 66.2: 12.29
+	Sc
		687985 IMB3_YEAST (1-1089): 3.51e-179: 555: 100.00		NUP49_YEAST (3-140): 3.57e-10: 66.1: 29.68
+	Sc
		687968 IMB3_YEAST (1-1089): 3.51e-179: 555: 100.00		NUP42_YEAST (2-285): 1.65e-09: 63.8: 17.86
+	Sc
		687954 IMB3_YEAST (1-1089): 3.51e-179: 555: 100.00		NU159_YEAST (2-479): 6.29e-09: 62.7: 11.43
+	Ce
		136533 Q9N5V3_CAEEL (11-1083): 1.09e-144: 464: 24.30		O01576_CAEEL (3-367): 1.3e-16: 87.8: 20.83
+	Ce
		1341732 Q9N5V3_CAEEL (11-1083): 1.09e-144: 464: 24.30		Q9XWK3_CAEEL (4-179): 3.66e-12: 72.6: 28.89
+	Sc
		767712 IMB4_YEAST (7-1076): 8.52e-100: 342: 18.75		NU100_YEAST (45-542): 1.84e-14: 80.8: 14.10
+	Sc
		541885 IMB4_YEAST (7-1076): 8.52e-100: 342: 18.75		NSP1_YEAST (3-459): 5.33e-11: 69.3: 13.35
+	Sc
		767683 IMB4_YEAST (7-1076): 8.52e-100: 342: 18.75		NUP57_YEAST (118-368): 1.26e-10: 67.7: 15.33
+	Sc
		767713 IMB4_YEAST (7-1076): 8.52e-100: 342: 18.75		NU116_YEAST (43-484): 6.18e-10: 66.2: 12.29
+	Sc
		767710 IMB4_YEAST (7-1076): 8.52e-100: 342: 18.75		NUP49_YEAST (3-140): 3.57e-10: 66.1: 29.68
+	Sc
		767684 IMB4_YEAST (7-1076): 8.52e-100: 342: 18.75		NUP42_YEAST (2-285): 1.65e-09: 63.8: 17.86
+	Sc
		767656 IMB4_YEAST (7-1076): 8.52e-100: 342: 18.75		NU159_YEAST (2-479): 6.29e-09: 62.7: 11.43
+	Hs
		858024 TNPO1_HUMAN (293-1089): 1.13e-68: 250: 11.87		NUP98_HUMAN (1-435): 2.24e-14: 80.9: 13.29
+	Hs
		834652 TNPO1_HUMAN (293-1089): 1.13e-68: 250: 11.87		NU153_HUMAN (16-447): 4.54e-11: 70: 10.50
+	Hs
		727300 TNPO1_HUMAN (293-1089): 1.13e-68: 250: 11.87		NU214_HUMAN (14-341): 6.71e-11: 69.6: 16.43
+	Tt
		101907 G0SGZ5_CHATD (6-924): 2.31e-68: 250: 15.76		NU145_CHATD (7-472): 2.07e-10: 67.8: 12.30