HitPredict

Interactor 1: IMB3 (P32337)
Importin subunit beta-3 (Karyopherin subunit beta-3) (Karyopherin-121) (Protein secretion enhancer 1)
Gene: PSE1

Interactor 2: NUP49 (Q02199)
Nucleoporin NUP49/NSP49 (Nuclear pore protein NUP49/NSP49)
Gene: NUP49

Species: Saccharomyces cerevisiae S288C

Source: biogrid

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.58	0.60	0.595

Property	Details
Experiments	11387327, 22357553
Identification Methods	affinity chromatography technology, pull down
Interaction Type	physical association, direct interaction

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0006606 - protein import into nucleus GO:0008139 - nuclear localization sequence binding
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 1089 Sc			1 472
+	Sc
		687969 IMB3_YEAST (1-1089): 3.51e-179: 555: 100.00		NU145_YEAST (1-351): 5.19e-20: 95.7: 16.76
+	Sc
		687986 IMB3_YEAST (1-1089): 3.51e-179: 555: 100.00		NU100_YEAST (1-363): 1.45e-17: 87.9: 20.00
+	Sc
		687967 IMB3_YEAST (1-1089): 3.51e-179: 555: 100.00		NUP57_YEAST (17-256): 3.28e-17: 85.9: 32.67
+	Sc
		687954 IMB3_YEAST (1-1089): 3.51e-179: 555: 100.00		NU159_YEAST (2-419): 1.68e-10: 65.6: 12.88
+	Sc
		687987 IMB3_YEAST (1-1089): 3.51e-179: 555: 100.00		NU116_YEAST (1-276): 9.6e-09: 59.8: 20.85
+	Sc
		767710 IMB4_YEAST (7-1076): 8.52e-100: 342: 18.75		NUP49_YEAST (1-472): 2e-64: 217: 100.00
+	Ce
		1341732 Q9N5V3_CAEEL (11-1083): 1.09e-144: 464: 24.30		Q9XWK3_CAEEL (48-375): 6e-17: 85.2: 18.44
+	Ce
		136533 Q9N5V3_CAEEL (11-1083): 1.09e-144: 464: 24.30		O01576_CAEEL (1-253): 4.9e-09: 60.6: 18.36
+	Sc
		767712 IMB4_YEAST (7-1076): 8.52e-100: 342: 18.75		NU100_YEAST (1-363): 1.45e-17: 87.9: 20.00
+	Sc
		767683 IMB4_YEAST (7-1076): 8.52e-100: 342: 18.75		NUP57_YEAST (17-256): 3.28e-17: 85.9: 32.67
+	Sc
		767656 IMB4_YEAST (7-1076): 8.52e-100: 342: 18.75		NU159_YEAST (2-419): 1.68e-10: 65.6: 12.88
+	Sc
		767713 IMB4_YEAST (7-1076): 8.52e-100: 342: 18.75		NU116_YEAST (1-276): 9.6e-09: 59.8: 20.85
+	Hs
		858024 TNPO1_HUMAN (293-1089): 1.13e-68: 250: 11.87		NUP98_HUMAN (124-327): 9.57e-18: 88.7: 14.67
+	Hs
		834652 TNPO1_HUMAN (293-1089): 1.13e-68: 250: 11.87		NU153_HUMAN (1-243): 4.4e-17: 86.7: 18.00
+	Hs
		727300 TNPO1_HUMAN (293-1089): 1.13e-68: 250: 11.87		NU214_HUMAN (9-247): 6.29e-16: 82.9: 22.39
+	Hs
		155553 TNPO2_HUMAN (214-1089): 4.77e-66: 242: 11.98		NUP98_HUMAN (124-327): 9.57e-18: 88.7: 14.67
+	Hs
		155550 TNPO2_HUMAN (214-1089): 4.77e-66: 242: 11.98		NU153_HUMAN (1-243): 4.4e-17: 86.7: 18.00
+	Tt
		101907 G0SGZ5_CHATD (6-924): 2.31e-68: 250: 15.76		NU145_CHATD (18-328): 2.36e-10: 65.2: 20.67
+	Ce
		248176 O62332_CAEEL (246-1088): 2.4e-63: 234: 11.19		Q21295_CAEEL (53-210): 4.88e-11: 67.1: 18.45
+	Ce
		248185 O62332_CAEEL (246-1088): 2.4e-63: 234: 11.19		Q9U3B9_CAEEL (37-275): 6.81e-10: 63.3: 14.23