HitPredict

Interactor 1: ERG3 (P32353)
Delta(7)-sterol 5(6)-desaturase ERG3 (EC 1.14.19.20) (C-5 sterol desaturase ERG3) (Ergosterol Delta(5,6) desaturase ERG3) (Ergosterol biosynthetic protein 3) (Sterol-C5-desaturase)
Gene: ERG3

Interactor 2: ERG25 (P53045)
C-4 methylsterol oxidase ERG25 (EC 1.14.18.-) (Ergosterol biosynthetic protein 25) (Sterol-C4-methyl oxidase ERG25) (SMO)
Gene: ERG25

Species: Saccharomyces cerevisiae S288C

Source: mint

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.66 0.60 0.632

The method score is based on:

Property Details
Experiments 18467557, 16300994
Identification Methods protein complementation assay, ubiquitin reconstruction, dihydrofolate reductase reconstruction
Interaction Type direct interaction, physical association

The annotation score is based on:

Property Details
Interacting Pfam domains -
Common GO terms GO:0000170 - sphingosine hydroxylase activity
GO:0000248 - C-5 sterol desaturase activity
GO:0000254 - C-4 methylsterol oxidase activity
GO:0005506 - iron ion binding
GO:0005789 - endoplasmic reticulum membrane
and 3 others

more...
Homologous interactions 4

Homologous interactions

Color coding for hit scores

1 365
Sc

1 309
+ Sc
+ Sc
+ At
+ At

Service provided by Combinatics, Japan

Last updated: 15 Jul 2024