Interactor 1: IRE1 (P32361)
Serine/threonine-protein kinase/endoribonuclease IRE1 (Endoplasmic reticulum-to-nucleus signaling 1) [Includes: Serine/threonine-protein kinase (EC 2.7.11.1); Endoribonuclease (EC 3.1.26.-)]
Gene: IRE1

Interactor 2: TDA1 (Q03533)
Serine/threonine-protein kinase TDA1 (Topoisomerase I damage affected protein 1) (EC 2.7.11.1)
Gene: TDA1

Species: Saccharomyces cerevisiae S288C

Source: biogrid

Category: High-throughput

Confidence: High

Method score Annotation score Interaction score
0.38 1.00 0.618

The method score is based on:

Property Details
Experiments 37968396
Identification Methods affinity chromatography technology
Interaction Type physical association

The annotation score is based on:

Property Details
Interacting Pfam domains Pkinase~Pkinase, Pkinase~Ribonuc_2-5A
Common GO terms GO:0004672 - protein kinase activity
GO:0004674 - protein serine/threonine kinase activity
GO:0005524 - ATP binding
GO:0005634 - nucleus
GO:0106310 - protein serine kinase activity
Homologous interactions 20

Homologous interactions (Top 20)

Color coding for hit scores

1 1115
Sc

1 586
+ At
+ At
+ Gm
+ At
+ At
+ Hs
+ Hs
+ At
+ Hs
+ Rn
+ Mm
+ Hs
+ At
+ Hs
+ At
+ Hs
+ At
+ Hs
+ Rn
+ Hs

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Last updated: 15 Jul 2024