HitPredict

Interactor 1: VA0D (P32366)
V-type proton ATPase subunit d (V-ATPase subunit d) (V-ATPase 39 kDa subunit) (V-ATPase subunit M39) (Vacuolar proton pump subunit d)
Gene: VMA6

Interactor 2: VPP1 (P32563)
V-type proton ATPase subunit a, vacuolar isoform (V-ATPase a 1 subunit) (V-ATPase 95 kDa subunit) (Vacuolar pH protein 1) (Vacuolar proton pump a subunit) (Vacuolar proton translocating ATPase subunit a 1)
Gene: VPH1

Species: Saccharomyces cerevisiae S288C

Source: mint

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.96 1.00 0.983

The method score is based on:

Property Details
Experiments 11592965, 19081055, 11823419, 16554755, 16429126, 26416888, 30910982, 19473972, 18467557, 19289121, 37968396, 32424347
Identification Methods coimmunoprecipitation, anti tag coimmunoprecipitation, affinity chromatography technology, pull down, biochemical, protein complementation assay, dihydrofolate reductase reconstruction, tandem affinity purification, surface plasmon resonance
Interaction Type physical association, direct interaction, association

The annotation score is based on:

Property Details
Interacting Pfam domains V_ATPase_I~vATP-synt_AC39
Common GO terms GO:0000220 - vacuolar proton-transporting V-type ATPase, V0 domain
GO:0000329 - fungal-type vacuole membrane
GO:0007035 - vacuolar acidification
GO:0016471 - vacuolar proton-transporting V-type ATPase complex
GO:0046961 - proton-transporting ATPase activity, rotational mechanism
and 1 others

more...
Homologous interactions 12

Homologous interactions

Color coding for hit scores

1 345
Sc

1 840
+ Hs
+ Hs
+ Hs
+ Hs
+ Mm
+ Dm
+ Hs
+ Dm
+ Hs
+ Hs
+ Hs
+ Sc

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Last updated: 15 Jul 2024