HitPredict

Interactor 1: RAD4 (P32372)
S-M checkpoint control protein rad4 (P74) (Protein cut5)
Gene: RAD4

Interactor 2: RHP9 (P87074)
DNA repair protein crb2 (Checkpoint mediator protein crb2) (Cut5-repeat binding protein 2) (RAD9 protein homolog)
Gene: crb2

Species: Schizosaccharomyces pombe 972h-

Source: intact

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.91 0.90 0.909

The method score is based on:

Property Details
Experiments 24074952, 16778077, 9407031, 15229228, 24663817, 14739927
Identification Methods pull down, two hybrid, x-ray crystallography, affinity chromatography technology, tandem affinity purification
Interaction Type direct interaction, association, physical association

The annotation score is based on:

Property Details
Interacting Pfam domains BRCT~BRCT, BRCT~PTCB-BRCT
Common GO terms GO:0000785 - chromatin
GO:0005634 - nucleus
GO:0007095 - mitotic G2 DNA damage checkpoint signaling
GO:0033314 - mitotic DNA replication checkpoint signaling
GO:0035861 - site of double-strand break
and 1 others

more...
Homologous interactions 0

Service provided by Combinatics, Japan

Last updated: 15 Jul 2024