HitPredict

Interactor 1: ARP2 (P32381)
Actin-related protein 2 (Actin-like protein ARP2) (Actin-like protein 2)
Gene: ARP2

Interactor 2: VRP1 (P37370)
Verprolin
Gene: VRP1

Species: Saccharomyces cerevisiae S288C

Source: mint

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.62	1.00	0.793

Property	Details
Experiments	18467557, 37968396
Identification Methods	protein complementation assay, affinity chromatography technology, dihydrofolate reductase reconstruction
Interaction Type	direct interaction, physical association

Property	Details
Interacting Pfam domains	Actin~WH2
Common GO terms	GO:0030479 - actin cortical patch
Homologous interactions	10

Homologous interactions

Color coding for hit scores

	1 391 Sc			1 817
+	Hs
		554290 ACTA_HUMAN (2-389): 0: 558: 45.62		MUC1_HUMAN (52-810): 3.67e-45: 177: 11.30
+	Sc
		741556 ACT_YEAST (1-389): 0: 557: 44.87		VRP1_YEAST (1-817): 1.29e-36: 150: 100.00
+	Hs
		932156 ACTC_HUMAN (2-389): 0: 559: 45.88		MDC1_HUMAN (23-817): 1.05e-25: 116: 10.81
+	Dm
		501445 ACT5_DROME (2-389): 0: 563: 46.13		CPN_DROME (376-816): 6.79e-14: 77.8: 12.90
+	Hs
		891853 ACTB_HUMAN (2-389): 0: 566: 46.39		SRCAP_HUMAN (191-817): 3.96e-12: 72.4: 9.73
+	Hs
		929905 ACTG_HUMAN (2-389): 0: 566: 46.13		SRCAP_HUMAN (191-817): 3.96e-12: 72.4: 9.73
+	Dm
		501503 ACT1_DROME (2-389): 0: 564: 45.62		Q86BH2_DROME (29-797): 4.21e-11: 69.3: 9.36
+	Hs
		932219 ACTC_HUMAN (2-389): 0: 559: 45.88		SRCAP_HUMAN (191-817): 3.96e-12: 72.4: 9.73
+	Hs
		932341 ACTC_HUMAN (2-389): 0: 559: 45.88		CIC_HUMAN (10-707): 1.45e-10: 67.4: 13.59
+	Hs
		203220 ACTC_HUMAN (2-389): 0: 559: 45.88		SYNJ1_HUMAN (63-493): 8.24e-10: 65.1: 11.49