HitPredict

Interactor 1: ARP2 (P32381)
Actin-related protein 2 (Actin-like protein ARP2) (Actin-like protein 2)
Gene: ARP2

Interactor 2: BNI1 (P41832)
Protein BNI1 (Pointed projection formation protein 3) (Sensitive to high expression protein 5) (Synthetic lethal 39)
Gene: BNI1

Species: Saccharomyces cerevisiae S288C

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.63	1.00	0.799

Property	Details
Experiments	11805837, 24133141
Identification Methods	anti tag coimmunoprecipitation, affinity chromatography technology, pull down
Interaction Type	physical association, direct interaction, association

Property	Details
Interacting Pfam domains	Actin~FH2
Common GO terms	GO:0045010 - actin nucleation
Homologous interactions	19

Homologous interactions

Color coding for hit scores

	1 391 Sc			1 1953
+	Sc
		784637 ACT_YEAST (1-389): 0: 557: 44.87		BNI1_YEAST (1-1953): 0: 1031: 100.00
+	Hs
		892145 ACTB_HUMAN (2-389): 0: 566: 46.39		FHOD1_HUMAN (966-1921): 2.09e-103: 363: 14.13
+	Hs
		930071 ACTG_HUMAN (2-389): 0: 566: 46.13		FHOD1_HUMAN (966-1921): 2.09e-103: 363: 14.13
+	Hs
		892076 ACTB_HUMAN (2-389): 0: 566: 46.39		FMN2_HUMAN (1319-1782): 4.86e-89: 325: 16.94
+	Hs
		930029 ACTG_HUMAN (2-389): 0: 566: 46.13		FMN2_HUMAN (1319-1782): 4.86e-89: 325: 16.94
+	Hs
		932414 ACTC_HUMAN (2-389): 0: 559: 45.88		FMN2_HUMAN (1319-1782): 4.86e-89: 325: 16.94
+	Sc
		773864 ACT_YEAST (1-389): 0: 557: 44.87		BNR1_YEAST (1316-1848): 2.35e-86: 314: 29.46
+	Dm
		361147 ACT2_DROME (2-389): 0: 563: 45.62		Q8SY43_DROME (992-1771): 1.09e-83: 304: 12.36
+	Sp
		501585 ACT_SCHPO (2-389): 0: 559: 45.62		CDC12_SCHPO (37-958): 1.06e-80: 298: 15.01
+	Hs
		929974 ACTG_HUMAN (2-389): 0: 566: 46.13		FMNL2_HUMAN (158-716): 5.71e-69: 256: 12.79
+	Hs
		915429 ACTA_HUMAN (2-389): 0: 558: 45.62		FMNL3_HUMAN (179-726): 1.53e-69: 257: 13.23
+	Hs
		237575 ACTB_HUMAN (2-389): 0: 566: 46.39		DIAP1_HUMAN (222-805): 3.01e-63: 240: 13.61
+	Hs
		892064 ACTB_HUMAN (2-389): 0: 566: 46.39		DIAP3_HUMAN (219-765): 1.59e-61: 234: 12.39
+	Hs
		237587 ACTC_HUMAN (2-389): 0: 559: 45.88		DIAP1_HUMAN (222-805): 3.01e-63: 240: 13.61
+	Hs
		892135 ACTB_HUMAN (2-389): 0: 566: 46.39		DAAM1_HUMAN (255-804): 1.25e-53: 208: 12.90
+	Hs
		891803 ACTB_HUMAN (2-389): 0: 566: 46.39		INF2_HUMAN (349-686): 3.46e-17: 90.5: 12.43
+	Hs
		929884 ACTG_HUMAN (2-389): 0: 566: 46.13		INF2_HUMAN (349-686): 3.46e-17: 90.5: 12.43
+	Hs
		932188 ACTC_HUMAN (2-389): 0: 559: 45.88		INF2_HUMAN (349-686): 3.46e-17: 90.5: 12.43
+	Hs
		896906 ARP2_HUMAN (7-389): 0: 549: 67.89		INF2_HUMAN (349-686): 3.46e-17: 90.5: 12.43