Interactor 1: ARP2 (P32381)
Actin-related protein 2 (Actin-like protein ARP2) (Actin-like protein 2)
Gene: ARP2

Interactor 2: ARPC2 (P53731)
Actin-related protein 2/3 complex subunit 2 (Arp2/3 complex 34 kDa subunit) (p34-ARC)
Gene: ARC35

Species: Saccharomyces cerevisiae S288C

Source: mint

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.94 1.00 0.972

The method score is based on:

Property Details
Experiments 11331312, 11805837, 11805826, 16429126, 18381280, 23583819, 18467557, 37968396, 20207164
Identification Methods affinity chromatography technology, anti tag coimmunoprecipitation, tandem affinity purification, biochemical, protein complementation assay, dihydrofolate reductase reconstruction
Interaction Type physical association, association, direct interaction

The annotation score is based on:

Property Details
Interacting Pfam domains Actin~P34-Arc
Common GO terms GO:0005885 - Arp2/3 protein complex
GO:0015629 - actin cytoskeleton
GO:0030479 - actin cortical patch
GO:0034314 - Arp2/3 complex-mediated actin nucleation
GO:0045010 - actin nucleation
and 2 others

more...

Homologous interactions 6

Homologous interactions

Color coding for hit scores

1 391
Sc

1 342
+ Sp
+ Hs
+ Hs
+ Dm
+ Hs
+ Dm

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Last updated: 15 Jul 2024