HitPredict

Interactor 1: ARP2 (P32381)
Actin-related protein 2 (Actin-like protein ARP2) (Actin-like protein 2)
Gene: ARP2

Interactor 2: RUVB1 (Q03940)
RuvB-like protein 1 (RUVBL1) (EC 3.6.4.12) (TIP49-homology protein 1) (TIP49a homolog)
Gene: RVB1

Species: Saccharomyces cerevisiae S288C

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.62	1.00	0.789

Property	Details
Experiments	11805837, 26831523
Identification Methods	anti tag coimmunoprecipitation, affinity chromatography technology
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	Actin~TIP49
Common GO terms	GO:0005524 - ATP binding GO:0016887 - ATP hydrolysis activity
Homologous interactions	10

Homologous interactions

Color coding for hit scores

	1 391 Sc			1 463
+	Hs
		892123 ACTB_HUMAN (2-389): 0: 566: 46.39		RUVB1_HUMAN (2-461): 0: 682: 67.61
+	Hs
		930058 ACTG_HUMAN (2-389): 0: 566: 46.13		RUVB1_HUMAN (2-461): 0: 682: 67.61
+	Hs
		932463 ACTC_HUMAN (2-389): 0: 559: 45.88		RUVB1_HUMAN (2-461): 0: 682: 67.61
+	Sc
		887667 ACT_YEAST (1-389): 0: 557: 44.87		RUVB1_YEAST (1-463): 0: 682: 100.00
+	Hs
		897003 ARP2_HUMAN (7-389): 0: 549: 67.89		RUVB1_HUMAN (2-461): 0: 682: 67.61
+	Dm
		501453 ACT5_DROME (2-389): 0: 563: 46.13		RUVB1_DROME (15-461): 0: 648: 66.89
+	Hs
		892121 ACTB_HUMAN (2-389): 0: 566: 46.39		RUVB2_HUMAN (1-458): 0: 637: 41.09
+	Hs
		930057 ACTG_HUMAN (2-389): 0: 566: 46.13		RUVB2_HUMAN (1-458): 0: 637: 41.09
+	Hs
		932462 ACTC_HUMAN (2-389): 0: 559: 45.88		RUVB2_HUMAN (1-458): 0: 637: 41.09
+	Sc
		887725 ACT_YEAST (1-389): 0: 557: 44.87		RUVB2_YEAST (15-463): 0: 622: 41.15