HitPredict

Interactor 1: ARP2 (P32381)
Actin-related protein 2 (Actin-like protein ARP2) (Actin-like protein 2)
Gene: ARP2

Interactor 2: CORO (Q06440)
Coronin-like protein
Gene: CRN1

Species: Saccharomyces cerevisiae S288C

Source: biogrid

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.73	1.00	0.855

Property	Details
Experiments	12499356, 21454476, 20207164
Identification Methods	cosedimentation through density gradient, coimmunoprecipitation, pull down, affinity chromatography technology
Interaction Type	physical association, direct interaction

Property	Details
Interacting Pfam domains	Actin~WD40
Common GO terms	GO:0030479 - actin cortical patch GO:0051015 - actin filament binding
Homologous interactions	12

Homologous interactions

Color coding for hit scores

	1 391 Sc			1 651
+	Sc
		887686 ACT_YEAST (1-389): 0: 557: 44.87		CORO_YEAST (1-651): 8.36e-147: 442: 100.00
+	Hs
		892108 ACTB_HUMAN (2-389): 0: 566: 46.39		COR1C_HUMAN (3-487): 2.38e-92: 295: 36.33
+	Hs
		930051 ACTG_HUMAN (2-389): 0: 566: 46.13		COR1C_HUMAN (3-487): 2.38e-92: 295: 36.33
+	Hs
		932449 ACTC_HUMAN (2-389): 0: 559: 45.88		COR1C_HUMAN (3-487): 2.38e-92: 295: 36.33
+	Hs
		896996 ARP2_HUMAN (7-389): 0: 549: 67.89		COR1C_HUMAN (3-487): 2.38e-92: 295: 36.33
+	Hs
		932355 ACTC_HUMAN (2-389): 0: 559: 45.88		COR1B_HUMAN (1-487): 4.21e-88: 285: 34.89
+	Hs
		891943 ACTB_HUMAN (2-389): 0: 566: 46.39		COR2A_HUMAN (1-477): 1.03e-78: 261: 36.81
+	Hs
		929956 ACTG_HUMAN (2-389): 0: 566: 46.13		COR2A_HUMAN (1-477): 1.03e-78: 261: 36.81
+	Hs
		884627 ACTB_HUMAN (2-389): 0: 566: 46.39		CORO7_HUMAN (7-431): 1.7e-67: 239: 26.62
+	Hs
		891660 ACTB_HUMAN (2-389): 0: 566: 46.39		WDR5_HUMAN (262-452): 3.45e-23: 102: 5.70
+	Hs
		903110 ACTG_HUMAN (2-389): 0: 566: 46.13		WDR5_HUMAN (262-452): 3.45e-23: 102: 5.70
+	Hs
		932318 ACTC_HUMAN (2-389): 0: 559: 45.88		SNR40_HUMAN (314-524): 2.37e-09: 61.7: 11.27