HitPredict

Interactor 1: ARP2 (P32381)
Actin-related protein 2 (Actin-like protein ARP2) (Actin-like protein 2)
Gene: ARP2

Interactor 2: AIM7 (Q12156)
Protein AIM7 (Altered inheritance rate of mitochondria protein 7)
Gene: AIM7

Species: Saccharomyces cerevisiae S288C

Source: mint

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.73	1.00	0.857

Property	Details
Experiments	23727094, 30042427, 18467557
Identification Methods	pull down, protein complementation assay, dihydrofolate reductase reconstruction
Interaction Type	direct interaction, physical association

Property	Details
Interacting Pfam domains	Actin~Cofilin_ADF
Common GO terms	GO:0030479 - actin cortical patch
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 391 Sc			1 149
+	At
		862533 ACT7_ARATH (2-389): 0: 583: 46.13		ADF6_ARATH (3-145): 1.57e-46: 149: 16.08
+	Hs
		891649 ACTB_HUMAN (2-389): 0: 566: 46.39		DEST_HUMAN (1-146): 3.33e-50: 159: 16.77
+	Hs
		894652 ACTG_HUMAN (2-389): 0: 566: 46.13		DEST_HUMAN (1-146): 3.33e-50: 159: 16.77
+	Hs
		894665 Q1KLZ0_HUMAN (2-389): 0: 566: 46.39		DEST_HUMAN (1-146): 3.33e-50: 159: 16.77
+	Hs
		618038 ACTB_HUMAN (2-389): 0: 566: 46.39		COF1_HUMAN (1-146): 3.06e-46: 149: 18.59
+	Hs
		618049 ACTG_HUMAN (2-389): 0: 566: 46.13		COF1_HUMAN (1-146): 3.06e-46: 149: 18.59
+	Hs
		618096 Q1KLZ0_HUMAN (2-389): 0: 566: 46.39		COF1_HUMAN (1-146): 3.06e-46: 149: 18.59
+	Hs
		1092828 Q1KLZ0_HUMAN (2-389): 0: 566: 46.39		Q549N0_HUMAN (1-146): 3.41e-45: 147: 19.87
+	Hs
		891817 ACTB_HUMAN (2-389): 0: 566: 46.39		Q549N0_HUMAN (1-146): 3.41e-45: 147: 19.87
+	Hs
		892124 ACTB_HUMAN (2-389): 0: 566: 46.39		COF2_HUMAN (1-146): 3.41e-45: 147: 19.87
+	Hs
		929891 ACTG_HUMAN (2-389): 0: 566: 46.13		Q549N0_HUMAN (1-146): 3.41e-45: 147: 19.87
+	Hs
		930059 ACTG_HUMAN (2-389): 0: 566: 46.13		COF2_HUMAN (1-146): 3.41e-45: 147: 19.87
+	Sp
		143281 ARP2_SCHPO (6-391): 0: 590: 72.80		GMF1_SCHPO (2-146): 2.96e-32: 113: 28.28
+	Hs
		891650 ACTB_HUMAN (2-389): 0: 566: 46.39		GMFB_HUMAN (6-146): 8.85e-39: 129: 24.11
+	Hs
		894697 ACTG_HUMAN (2-389): 0: 566: 46.13		GMFB_HUMAN (6-146): 8.85e-39: 129: 24.11
+	Ce
		501473 ACT4_CAEEL (2-389): 0: 567: 46.39		ADF1_CAEEL (1-149): 3.36e-18: 79: 13.86
+	Hs
		891834 ACTB_HUMAN (2-389): 0: 566: 46.39		TWF2_HUMAN (13-149): 2.65e-11: 61.7: 19.42
+	Hs
		929897 ACTG_HUMAN (2-389): 0: 566: 46.13		TWF2_HUMAN (13-149): 2.65e-11: 61.7: 19.42
+	Hs
		891728 ACTB_HUMAN (2-389): 0: 566: 46.39		TWF1_HUMAN (3-146): 6.61e-10: 57.8: 17.12
+	Hs
		929835 ACTG_HUMAN (2-389): 0: 566: 46.13		TWF1_HUMAN (3-146): 6.61e-10: 57.8: 17.12