HitPredict

Interactor 1: A8WFL0 (A8WFL0)
LIM zinc-binding domain-containing protein
Gene: prkl-1

Interactor 2: SRC1 (G5EE56)
Tyrosine protein-kinase src-1 (EC 2.7.10.2) (SRC oncogene related protein 1)
Gene: src-1

Species: Caenorhabditis elegans

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.59	0.60	0.595

Property	Details
Experiments	26780296, 23549480
Identification Methods	two hybrid
Interaction Type	direct interaction, physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0046872 - metal ion binding
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 409 Ce			1 533
+	Ce
		106634 H2KYA1_CAEEL (1-409): 1.7e-88: 279: 91.20		SRC1_CAEEL (1-533): 0: 579: 100.00
+	Hs
		217005 PRIC3_HUMAN (15-273): 1.3e-57: 200: 34.35		FYN_HUMAN (1-530): 0: 547: 49.26
+	Hs
		217008 PRIC3_HUMAN (15-273): 1.3e-57: 200: 34.35		SRC_HUMAN (1-530): 0: 544: 48.45
+	Hs
		150505 ABLM1_HUMAN (20-401): 1.89e-54: 194: 16.43		LYN_HUMAN (1-529): 1.41e-178: 514: 43.02
+	Hs
		217004 PRIC3_HUMAN (15-273): 1.3e-57: 200: 34.35		ABL1_HUMAN (42-525): 3.28e-165: 499: 39.43
+	Ce
		106629 G5EFG1_CAEEL (94-213): 4.89e-24: 106: 24.59		SRC1_CAEEL (1-533): 0: 579: 100.00
+	Hs
		522967 FHL1_HUMAN (63-264): 3.57e-33: 128: 18.72		SRC_HUMAN (1-530): 0: 544: 48.45
+	Hs
		254384 LDB3_HUMAN (95-226): 1.22e-27: 117: 25.76		SRC_HUMAN (1-530): 0: 544: 48.45
+	Hs
		238957 LPXN_HUMAN (5-219): 3.71e-49: 172: 15.81		BTK_HUMAN (1-525): 8.72e-157: 463: 32.32
+	Hs
		412085 PAXI_HUMAN (3-94): 1.22e-17: 86.9: 15.22		FYN_HUMAN (1-530): 0: 547: 49.26
+	Hs
		433288 PAXI_HUMAN (3-94): 1.22e-17: 86.9: 15.22		YES_HUMAN (1-530): 0: 546: 48.28
+	Mm
		403454 PAXI_MOUSE (3-94): 8.36e-18: 87.3: 15.22		SRC_MOUSE (1-530): 0: 544: 48.35
+	Ce
		107567 G5EFG1_CAEEL (94-213): 4.89e-24: 106: 24.59		SRC2_CAEEL (1-532): 0: 524: 43.15
+	Hs
		442793 PAXI_HUMAN (3-94): 1.22e-17: 86.9: 15.22		HCK_HUMAN (1-529): 0: 525: 44.34
+	Hs
		411641 PAXI_HUMAN (3-94): 1.22e-17: 86.9: 15.22		LCK_HUMAN (1-530): 3.31e-180: 518: 43.88
+	Hs
		433646 PAXI_HUMAN (3-94): 1.22e-17: 86.9: 15.22		LYN_HUMAN (1-529): 1.41e-178: 514: 43.02
+	Mm
		337635 PAXI_MOUSE (3-94): 8.36e-18: 87.3: 15.22		ABL1_MOUSE (42-525): 1.53e-165: 500: 39.43
+	Hs
		337395 PAXI_HUMAN (3-94): 1.22e-17: 86.9: 15.22		ABL1_HUMAN (42-525): 3.28e-165: 499: 39.43
+	Ce
		107570 G5EFG1_CAEEL (94-213): 4.89e-24: 106: 24.59		ABL1_CAEEL (11-525): 4.92e-152: 467: 36.13
+	Ce
		106914 G5EEL1_CAEEL (94-213): 7.72e-24: 105: 24.59		ABL1_CAEEL (11-525): 4.92e-152: 467: 36.13