HitPredict

Interactor 1: NAC1 (P32418)
Sodium/calcium exchanger 1 (Na(+)/Ca(2+)-exchange protein 1) (Solute carrier family 8 member 1)
Gene: SLC8A1

Interactor 2: S10AA (P60903)
Protein S100-A10 (Calpactin I light chain) (Calpactin-1 light chain) (Cellular ligand of annexin II) (S100 calcium-binding protein A10) (p10 protein) (p11)
Gene: S100A10

Species: Homo sapiens

Source: intact

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.41	0.60	0.501

Property	Details
Experiments	31837246
Identification Methods	fluorescence polarization spectroscopy
Interaction Type	direct interaction

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005509 - calcium ion binding GO:0005886 - plasma membrane GO:0044325 - transmembrane transporter binding
Homologous interactions	18

Homologous interactions

Color coding for hit scores

	1 973 Hs			1 97
+	Hs
		615205 NAC1_HUMAN (1-973): 0: 1131: 100.00		S10A1_HUMAN (1-91): 7.71e-34: 113: 45.75
+	Hs
		689707 NAC1_HUMAN (1-973): 0: 1131: 100.00		S100Z_HUMAN (1-96): 9.6e-33: 111: 45.46
+	Hs
		685156 NAC1_HUMAN (1-973): 0: 1131: 100.00		S10AB_HUMAN (2-89): 4.9e-32: 109: 38.46
+	Hs
		638928 NAC1_HUMAN (1-973): 0: 1131: 100.00		S100P_HUMAN (3-87): 5.8e-31: 106: 45.46
+	Hs
		416365 NAC1_HUMAN (1-973): 0: 1131: 100.00		S10A9_HUMAN (3-96): 8.76e-29: 101: 29.59
+	Hs
		642918 NAC1_HUMAN (1-973): 0: 1131: 100.00		S10A4_HUMAN (1-87): 5.03e-29: 101: 35.56
+	Hs
		689700 NAC1_HUMAN (1-973): 0: 1131: 100.00		S10A3_HUMAN (1-89): 7.96e-29: 101: 27.17
+	Hs
		661206 NAC1_HUMAN (1-973): 0: 1131: 100.00		S10A2_HUMAN (1-87): 6.38e-28: 98.8: 36.67
+	Hs
		380746 NAC1_HUMAN (1-973): 0: 1131: 100.00		S100B_HUMAN (3-87): 2.3e-26: 94.6: 37.50
+	Hs
		689703 NAC1_HUMAN (1-973): 0: 1131: 100.00		S10AC_HUMAN (3-89): 1.55e-24: 89.9: 31.11
+	Hs
		689699 NAC1_HUMAN (1-973): 0: 1131: 100.00		S10A5_HUMAN (1-92): 1.15e-23: 88: 30.53
+	Hs
		396691 NAC1_HUMAN (1-973): 0: 1131: 100.00		S10A8_HUMAN (1-93): 1.69e-23: 87.6: 25.00
+	Hs
		416580 NAC1_HUMAN (1-973): 0: 1131: 100.00		S10A6_HUMAN (1-88): 2.47e-23: 86.9: 25.28
+	Hs
		689706 NAC1_HUMAN (1-973): 0: 1131: 100.00		S1A7A_HUMAN (3-96): 1.02e-21: 83: 23.96
+	Hs
		678415 NAC1_HUMAN (1-973): 0: 1131: 100.00		S10A7_HUMAN (3-96): 1.13e-20: 80.7: 21.88
+	Hs
		689709 NAC1_HUMAN (1-973): 0: 1131: 100.00		S10AE_HUMAN (3-81): 4.74e-19: 76.5: 28.40
+	Hs
		689708 NAC1_HUMAN (1-973): 0: 1131: 100.00		S10AD_HUMAN (3-81): 1.23e-18: 75.3: 30.49
+	Hs
		666669 NAC1_HUMAN (1-973): 0: 1131: 100.00		S100G_HUMAN (4-81): 6.67e-15: 65.3: 29.63