HitPredict

Interactor 1: NAC1 (P32418)
Sodium/calcium exchanger 1 (Na(+)/Ca(2+)-exchange protein 1) (Solute carrier family 8 member 1)
Gene: SLC8A1

Interactor 2: S1A7A (Q86SG5)
Protein S100-A7A (S100 calcium-binding protein A15) (S100 calcium-binding protein A7-like 1) (S100 calcium-binding protein A7A)
Gene: S100A7A

Species: Homo sapiens

Source: intact

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.41	0.60	0.501

Property	Details
Experiments	31837246
Identification Methods	fluorescence polarization spectroscopy
Interaction Type	direct interaction

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005509 - calcium ion binding
Homologous interactions	18

Homologous interactions

Color coding for hit scores

	1 973 Hs			1 101
+	Hs
		615205 NAC1_HUMAN (1-973): 0: 1131: 100.00		S10A1_HUMAN (2-94): 3.13e-33: 112: 20.83
+	Hs
		685156 NAC1_HUMAN (1-973): 0: 1131: 100.00		S10AB_HUMAN (2-95): 2.67e-33: 112: 35.05
+	Hs
		689702 NAC1_HUMAN (1-973): 0: 1131: 100.00		S10AA_HUMAN (2-90): 4.85e-33: 111: 24.72
+	Hs
		678415 NAC1_HUMAN (1-973): 0: 1131: 100.00		S10A7_HUMAN (1-101): 1.57e-31: 108: 94.06
+	Hs
		638928 NAC1_HUMAN (1-973): 0: 1131: 100.00		S100P_HUMAN (4-93): 2.49e-31: 107: 29.03
+	Hs
		689707 NAC1_HUMAN (1-973): 0: 1131: 100.00		S100Z_HUMAN (2-98): 1.65e-30: 105: 23.00
+	Hs
		416365 NAC1_HUMAN (1-973): 0: 1131: 100.00		S10A9_HUMAN (4-100): 6.42e-30: 104: 25.00
+	Hs
		642918 NAC1_HUMAN (1-973): 0: 1131: 100.00		S10A4_HUMAN (2-96): 3.14e-29: 102: 24.49
+	Hs
		661206 NAC1_HUMAN (1-973): 0: 1131: 100.00		S10A2_HUMAN (1-97): 8.23e-29: 101: 22.00
+	Hs
		689700 NAC1_HUMAN (1-973): 0: 1131: 100.00		S10A3_HUMAN (2-98): 5.69e-28: 99.2: 18.45
+	Hs
		380746 NAC1_HUMAN (1-973): 0: 1131: 100.00		S100B_HUMAN (4-93): 1.92e-26: 95: 24.73
+	Hs
		689703 NAC1_HUMAN (1-973): 0: 1131: 100.00		S10AC_HUMAN (4-93): 4.09e-26: 94.2: 24.73
+	Hs
		396691 NAC1_HUMAN (1-973): 0: 1131: 100.00		S10A8_HUMAN (2-96): 1.01e-25: 93.4: 23.47
+	Hs
		416580 NAC1_HUMAN (1-973): 0: 1131: 100.00		S10A6_HUMAN (2-92): 9.33e-25: 90.7: 24.47
+	Hs
		689699 NAC1_HUMAN (1-973): 0: 1131: 100.00		S10A5_HUMAN (2-94): 1.49e-24: 90.4: 22.92
+	Hs
		689709 NAC1_HUMAN (1-973): 0: 1131: 100.00		S10AE_HUMAN (4-84): 9.99e-20: 78.4: 21.69
+	Hs
		689708 NAC1_HUMAN (1-973): 0: 1131: 100.00		S10AD_HUMAN (4-84): 9.93e-20: 78: 20.24
+	Hs
		666669 NAC1_HUMAN (1-973): 0: 1131: 100.00		S100G_HUMAN (5-84): 1.1e-15: 67.2: 25.30