HitPredict

Interactor 1: NAC1 (P32418)
Sodium/calcium exchanger 1 (Na(+)/Ca(2+)-exchange protein 1) (Solute carrier family 8 member 1)
Gene: SLC8A1

Interactor 2: S10AE (Q9HCY8)
Protein S100-A14 (S100 calcium-binding protein A14) (S114)
Gene: S100A14

Species: Homo sapiens

Source: intact

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.41	0.60	0.501

Property	Details
Experiments	31837246
Identification Methods	fluorescence polarization spectroscopy
Interaction Type	direct interaction

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005509 - calcium ion binding GO:0055074 - calcium ion homeostasis
Homologous interactions	17

Homologous interactions

Color coding for hit scores

	1 973 Hs			1 104
+	Hs
		615205 NAC1_HUMAN (1-973): 0: 1131: 100.00		S10A1_HUMAN (16-95): 1.03e-27: 98.4: 26.19
+	Hs
		638928 NAC1_HUMAN (1-973): 0: 1131: 100.00		S100P_HUMAN (15-96): 4.1e-27: 96.9: 23.26
+	Hs
		685156 NAC1_HUMAN (1-973): 0: 1131: 100.00		S10AB_HUMAN (16-96): 1.36e-26: 96.1: 27.06
+	Hs
		416365 NAC1_HUMAN (1-973): 0: 1131: 100.00		S10A9_HUMAN (14-104): 5.38e-26: 94.5: 30.00
+	Hs
		689702 NAC1_HUMAN (1-973): 0: 1131: 100.00		S10AA_HUMAN (16-95): 4.45e-26: 94.5: 28.92
+	Hs
		689708 NAC1_HUMAN (1-973): 0: 1131: 100.00		S10AD_HUMAN (12-96): 2.07e-25: 92.6: 40.70
+	Hs
		689703 NAC1_HUMAN (1-973): 0: 1131: 100.00		S10AC_HUMAN (15-99): 5.28e-25: 91.5: 25.84
+	Hs
		642918 NAC1_HUMAN (1-973): 0: 1131: 100.00		S10A4_HUMAN (17-97): 2.93e-24: 89.9: 27.06
+	Hs
		380746 NAC1_HUMAN (1-973): 0: 1131: 100.00		S100B_HUMAN (15-97): 6.66e-24: 88.8: 27.59
+	Hs
		689707 NAC1_HUMAN (1-973): 0: 1131: 100.00		S100Z_HUMAN (16-95): 2e-23: 87.6: 21.43
+	Hs
		661206 NAC1_HUMAN (1-973): 0: 1131: 100.00		S10A2_HUMAN (16-95): 3.18e-23: 87.2: 25.00
+	Hs
		396691 NAC1_HUMAN (1-973): 0: 1131: 100.00		S10A8_HUMAN (15-98): 5.64e-23: 86.5: 21.59
+	Hs
		689699 NAC1_HUMAN (1-973): 0: 1131: 100.00		S10A5_HUMAN (16-94): 7.23e-22: 83.4: 23.75
+	Hs
		416580 NAC1_HUMAN (1-973): 0: 1131: 100.00		S10A6_HUMAN (17-92): 1e-21: 83: 26.92
+	Hs
		689700 NAC1_HUMAN (1-973): 0: 1131: 100.00		S10A3_HUMAN (17-97): 6.22e-21: 81.4: 18.82
+	Hs
		666669 NAC1_HUMAN (1-973): 0: 1131: 100.00		S100G_HUMAN (18-93): 3.3e-20: 79.1: 23.38
+	Hs
		678415 NAC1_HUMAN (1-973): 0: 1131: 100.00		S10A7_HUMAN (16-101): 4e-16: 69.1: 19.15