HitPredict

Interactor 1: GBP2 (P32456)
Guanylate-binding protein 2 (EC 3.6.5.-) (GTP-binding protein 2) (GBP-2) (HuGBP-2) (Guanine nucleotide-binding protein 2) (Interferon-induced guanylate-binding protein 2)
Gene: GBP2

Interactor 2: GBP7 (Q8N8V2)
Guanylate-binding protein 7 (EC 3.6.1.-) (EC 3.6.5.-) (GTP-binding protein 7) (GBP-7) (Guanine nucleotide-binding protein 7) (Guanylate-binding protein 4-like)
Gene: GBP7

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score Annotation score Interaction score
0.65 1.00 0.811

The method score is based on:

Property Details
Experiments 28514442, 33961781
Identification Methods affinity chromatography technology, anti tag coimmunoprecipitation
Interaction Type physical association, association

The annotation score is based on:

Property Details
Interacting Pfam domains GBP~GBP, GBP~GBP_C, GBP_C~GBP_C
Common GO terms GO:0003924 - GTPase activity
GO:0005525 - GTP binding
GO:0030659 - cytoplasmic vesicle membrane
GO:0031410 - cytoplasmic vesicle
GO:0042742 - defense response to bacterium
and 5 others

more...
Homologous interactions 14

Homologous interactions

Color coding for hit scores

1 591
Hs

1 638
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Last updated: 15 Jul 2024